LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Dactolisib | 10 | uM | LJP5 | 3 | M13 | 72 | hr | 1235 | 1317 | 4326 | 0.3044 | 0.0360 |
| MCF7 | Alpelisib | 0.04 | uM | LJP5 | 1 | N06 | 72 | hr | 1235 | 4253 | 4119 | 1.0325 | 1.0371 |
| MCF7 | Alpelisib | 0.04 | uM | LJP5 | 2 | N06 | 72 | hr | 1235 | 3496 | 4356 | 0.8025 | 0.7721 |
| MCF7 | Alpelisib | 0.04 | uM | LJP5 | 3 | N06 | 72 | hr | 1235 | 4096 | 4326 | 0.9467 | 0.9404 |
| MCF7 | Alpelisib | 0.12 | uM | LJP5 | 1 | N05 | 72 | hr | 1235 | 3253 | 4119 | 0.7897 | 0.7459 |
| MCF7 | Alpelisib | 0.12 | uM | LJP5 | 2 | N05 | 72 | hr | 1235 | 3644 | 4356 | 0.8365 | 0.8129 |
| MCF7 | Alpelisib | 0.12 | uM | LJP5 | 3 | N05 | 72 | hr | 1235 | 3455 | 4326 | 0.7986 | 0.7661 |
| MCF7 | Alpelisib | 0.37 | uM | LJP5 | 1 | N04 | 72 | hr | 1235 | 2742 | 4119 | 0.6657 | 0.5823 |
| MCF7 | Alpelisib | 0.37 | uM | LJP5 | 2 | N04 | 72 | hr | 1235 | 2668 | 4356 | 0.6125 | 0.5273 |
| MCF7 | Alpelisib | 0.37 | uM | LJP5 | 3 | N04 | 72 | hr | 1235 | 2632 | 4326 | 0.6084 | 0.5194 |
| MCF7 | Alpelisib | 1.11 | uM | LJP5 | 1 | N03 | 72 | hr | 1235 | 2185 | 4119 | 0.5304 | 0.3885 |
| MCF7 | Alpelisib | 1.11 | uM | LJP5 | 2 | N03 | 72 | hr | 1235 | 2393 | 4356 | 0.5493 | 0.4386 |
| MCF7 | Alpelisib | 1.11 | uM | LJP5 | 3 | N03 | 72 | hr | 1235 | 2185 | 4326 | 0.5050 | 0.3708 |
| MCF7 | Alpelisib | 3.33 | uM | LJP5 | 1 | N02 | 72 | hr | 1235 | 1655 | 4119 | 0.4018 | 0.1833 |
| MCF7 | Alpelisib | 3.33 | uM | LJP5 | 2 | N02 | 72 | hr | 1235 | 1654 | 4356 | 0.3797 | 0.1741 |
| MCF7 | Alpelisib | 3.33 | uM | LJP5 | 3 | N02 | 72 | hr | 1235 | 1787 | 4326 | 0.4130 | 0.2265 |
| MCF7 | Alpelisib | 10 | uM | LJP5 | 1 | N01 | 72 | hr | 1235 | 1073 | 4119 | 0.2605 | -0.0779 |
| MCF7 | Alpelisib | 10 | uM | LJP5 | 2 | N01 | 72 | hr | 1235 | 1074 | 4356 | 0.2465 | -0.0741 |
| MCF7 | Alpelisib | 10 | uM | LJP5 | 3 | N01 | 72 | hr | 1235 | 984 | 4326 | 0.2274 | -0.1182 |
| MCF7 | GDC-0980 | 0.04 | uM | LJP5 | 1 | K24 | 72 | hr | 1235 | 1270 | 4119 | 0.3083 | 0.0160 |
| MCF7 | GDC-0980 | 0.04 | uM | LJP5 | 2 | K24 | 72 | hr | 1235 | 1382 | 4356 | 0.3172 | 0.0636 |
| MCF7 | GDC-0980 | 0.04 | uM | LJP5 | 3 | K24 | 72 | hr | 1235 | 1531 | 4326 | 0.3539 | 0.1260 |
| MCF7 | GDC-0980 | 0.12 | uM | LJP5 | 1 | K23 | 72 | hr | 1235 | 1146 | 4119 | 0.2782 | -0.0423 |
| MCF7 | GDC-0980 | 0.12 | uM | LJP5 | 2 | K23 | 72 | hr | 1235 | 1202 | 4356 | 0.2759 | -0.0150 |
| MCF7 | GDC-0980 | 0.12 | uM | LJP5 | 3 | K23 | 72 | hr | 1235 | 1142 | 4326 | 0.2640 | -0.0425 |