LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | NVP-TAE684 | 0.04 | uM | LJP6 | 2 | K18 | 72 | hr | 1235 | 2474 | 4070 | 0.6078 | 0.4974 |
| MCF7 | NVP-TAE684 | 0.04 | uM | LJP6 | 3 | K18 | 72 | hr | 1235 | 2508 | 4126 | 0.6078 | 0.5023 |
| MCF7 | NVP-TAE684 | 0.12 | uM | LJP6 | 1 | K17 | 72 | hr | 1235 | 1452 | 3974 | 0.3654 | 0.1006 |
| MCF7 | NVP-TAE684 | 0.12 | uM | LJP6 | 2 | K17 | 72 | hr | 1235 | 1328 | 4070 | 0.3263 | 0.0429 |
| MCF7 | NVP-TAE684 | 0.12 | uM | LJP6 | 3 | K17 | 72 | hr | 1235 | 1452 | 4126 | 0.3519 | 0.0973 |
| MCF7 | NVP-TAE684 | 0.37 | uM | LJP6 | 1 | K16 | 72 | hr | 1235 | 1228 | 3974 | 0.3090 | -0.0036 |
| MCF7 | NVP-TAE684 | 0.37 | uM | LJP6 | 2 | K16 | 72 | hr | 1235 | 1154 | 4070 | 0.2835 | -0.0388 |
| MCF7 | NVP-TAE684 | 0.37 | uM | LJP6 | 3 | K16 | 72 | hr | 1235 | 1206 | 4126 | 0.2923 | -0.0137 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 1 | K15 | 72 | hr | 1235 | 1205 | 3974 | 0.3032 | -0.0147 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 2 | K15 | 72 | hr | 1235 | 925 | 4070 | 0.2273 | -0.1548 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 3 | K15 | 72 | hr | 1235 | 1067 | 4126 | 0.2586 | -0.0808 |
| MCF7 | NVP-TAE684 | 3.33 | uM | LJP6 | 1 | K14 | 72 | hr | 1235 | 949 | 3974 | 0.2388 | -0.1448 |
| MCF7 | NVP-TAE684 | 3.33 | uM | LJP6 | 2 | K14 | 72 | hr | 1235 | 1032 | 4070 | 0.2535 | -0.0993 |
| MCF7 | NVP-TAE684 | 3.33 | uM | LJP6 | 3 | K14 | 72 | hr | 1235 | 1082 | 4126 | 0.2622 | -0.0734 |
| MCF7 | NVP-TAE684 | 10 | uM | LJP6 | 1 | K13 | 72 | hr | 1235 | 1171 | 3974 | 0.2947 | -0.0313 |
| MCF7 | NVP-TAE684 | 10 | uM | LJP6 | 2 | K13 | 72 | hr | 1235 | 1142 | 4070 | 0.2806 | -0.0447 |
| MCF7 | NVP-TAE684 | 10 | uM | LJP6 | 3 | K13 | 72 | hr | 1235 | 1193 | 4126 | 0.2891 | -0.0199 |
| MCF7 | CGP60474 | 0.04 | uM | LJP6 | 1 | G06 | 72 | hr | 1235 | 508 | 3974 | 0.1278 | -0.4097 |
| MCF7 | CGP60474 | 0.04 | uM | LJP6 | 2 | G06 | 72 | hr | 1235 | 661 | 4070 | 0.1624 | -0.3048 |
| MCF7 | CGP60474 | 0.04 | uM | LJP6 | 3 | G06 | 72 | hr | 1235 | 643 | 4126 | 0.1558 | -0.3129 |
| MCF7 | CGP60474 | 0.04 | uM | LJP5 | 1 | F06 | 72 | hr | 1235 | 4521 | 4119 | 1.0975 | 1.1101 |
| MCF7 | CGP60474 | 0.04 | uM | LJP5 | 2 | F06 | 72 | hr | 1235 | 3978 | 4356 | 0.9132 | 0.9025 |
| MCF7 | CGP60474 | 0.04 | uM | LJP5 | 3 | F06 | 72 | hr | 1235 | 4134 | 4326 | 0.9555 | 0.9503 |
| MCF7 | CGP60474 | 0.12 | uM | LJP6 | 1 | G05 | 72 | hr | 1235 | 582 | 3974 | 0.1465 | -0.3601 |
| MCF7 | CGP60474 | 0.12 | uM | LJP6 | 2 | G05 | 72 | hr | 1235 | 630 | 4070 | 0.1548 | -0.3239 |