LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Sorafenib
0.12
uM
LJP6
 1
B11
 72
hr
 1235 3391 3974 0.8533 0.8203
MCF7 Sorafenib
0.12
uM
LJP6
 2
B11
 72
hr
 1235 3779 4070 0.9284 0.9155
MCF7 Sorafenib
0.12
uM
LJP6
 3
B11
 72
hr
 1235 3513 4126 0.8514 0.8233
MCF7 Sorafenib
0.37
uM
LJP6
 1
B10
 72
hr
 1235 3940 3974 0.9914 0.9898
MCF7 Sorafenib
0.37
uM
LJP6
 2
B10
 72
hr
 1235 4099 4070 1.0070 1.0082
MCF7 Sorafenib
0.37
uM
LJP6
 3
B10
 72
hr
 1235 3685 4126 0.8930 0.8741
MCF7 Sorafenib
1.11
uM
LJP6
 1
B09
 72
hr
 1235 3864 3974 0.9723 0.9669
MCF7 Sorafenib
1.11
uM
LJP6
 2
B09
 72
hr
 1235 3416 4070 0.8392 0.8063
MCF7 Sorafenib
1.11
uM
LJP6
 3
B09
 72
hr
 1235 3760 4126 0.9112 0.8959
MCF7 Sorafenib
3.33
uM
LJP6
 1
B08
 72
hr
 1235 3658 3974 0.9205 0.9040
MCF7 Sorafenib
3.33
uM
LJP6
 2
B08
 72
hr
 1235 3388 4070 0.8324 0.7977
MCF7 Sorafenib
3.33
uM
LJP6
 3
B08
 72
hr
 1235 3293 4126 0.7980 0.7568
MCF7 Sorafenib
10
uM
LJP6
 1
B07
 72
hr
 1235 1776 3974 0.4469 0.2403
MCF7 Sorafenib
10
uM
LJP6
 2
B07
 72
hr
 1235 1624 4070 0.3990 0.1723
MCF7 Sorafenib
10
uM
LJP6
 3
B07
 72
hr
 1235 1537 4126 0.3725 0.1338
MCF7 CP466722
0.04
uM
LJP5
 1
I12
 72
hr
 1235 4735 4119 1.1495 1.1670
MCF7 CP466722
0.04
uM
LJP5
 2
I12
 72
hr
 1235 4694 4356 1.0775 1.0838
MCF7 CP466722
0.04
uM
LJP5
 3
I12
 72
hr
 1235 5124 4326 1.1843 1.1962
MCF7 CP466722
0.12
uM
LJP5
 1
I11
 72
hr
 1235 4392 4119 1.0662 1.0752
MCF7 CP466722
0.12
uM
LJP5
 2
I11
 72
hr
 1235 4834 4356 1.1097 1.1178
MCF7 CP466722
0.12
uM
LJP5
 3
I11
 72
hr
 1235 4387 4326 1.0140 1.0154
MCF7 CP466722
0.37
uM
LJP5
 1
I10
 72
hr
 1235 4429 4119 1.0752 1.0852
MCF7 CP466722
0.37
uM
LJP5
 2
I10
 72
hr
 1235 5225 4356 1.1994 1.2104
MCF7 CP466722
0.37
uM
LJP5
 3
I10
 72
hr
 1235 4833 4326 1.1171 1.1263
MCF7 CP466722
1.11
uM
LJP5
 1
I09
 72
hr
 1235 4563 4119 1.1077 1.1213