LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Tozasertib
3.33
uM
LJP5
1
B14
72
hr
1235 1519 4119 0.3688 0.1263
MCF7 Tozasertib
3.33
uM
LJP5
2
B14
72
hr
1235 1359 4356 0.3120 0.0539
MCF7 Tozasertib
3.33
uM
LJP5
3
B14
72
hr
1235 1423 4326 0.3289 0.0813
MCF7 Tozasertib
10
uM
LJP5
1
B13
72
hr
1235 1347 4119 0.3270 0.0510
MCF7 Tozasertib
10
uM
LJP5
2
B13
72
hr
1235 1388 4356 0.3186 0.0662
MCF7 Tozasertib
10
uM
LJP5
3
B13
72
hr
1235 1221 4326 0.2822 -0.0065
MCF7 Imatinib
0.04
uM
LJP6
1
N18
72
hr
1235 4264 3974 1.0729 1.0853
MCF7 Imatinib
0.04
uM
LJP6
2
N18
72
hr
1235 4799 4070 1.1790 1.2009
MCF7 Imatinib
0.04
uM
LJP6
3
N18
72
hr
1235 4380 4126 1.0615 1.0698
MCF7 Imatinib
0.12
uM
LJP6
1
N17
72
hr
1235 4778 3974 1.2023 1.2310
MCF7 Imatinib
0.12
uM
LJP6
2
N17
72
hr
1235 4039 4070 0.9923 0.9910
MCF7 Imatinib
0.12
uM
LJP6
3
N17
72
hr
1235 4572 4126 1.1080 1.1214
MCF7 Imatinib
0.37
uM
LJP6
1
N16
72
hr
1235 4993 3974 1.2564 1.2900
MCF7 Imatinib
0.37
uM
LJP6
2
N16
72
hr
1235 4092 4070 1.0053 1.0062
MCF7 Imatinib
0.37
uM
LJP6
3
N16
72
hr
1235 4804 4126 1.1642 1.1826
MCF7 Imatinib
1.11
uM
LJP6
1
N15
72
hr
1235 4352 3974 1.0951 1.1107
MCF7 Imatinib
1.11
uM
LJP6
2
N15
72
hr
1235 4165 4070 1.0233 1.0269
MCF7 Imatinib
1.11
uM
LJP6
3
N15
72
hr
1235 4776 4126 1.1574 1.1753
MCF7 Imatinib
3.33
uM
LJP6
1
N14
72
hr
1235 4581 3974 1.1527 1.1759
MCF7 Imatinib
3.33
uM
LJP6
2
N14
72
hr
1235 3934 4070 0.9665 0.9608
MCF7 Imatinib
3.33
uM
LJP6
3
N14
72
hr
1235 4492 4126 1.0886 1.1000
MCF7 Imatinib
10
uM
LJP6
1
N13
72
hr
1235 3924 3974 0.9874 0.9850
MCF7 Imatinib
10
uM
LJP6
2
N13
72
hr
1235 3367 4070 0.8272 0.7912
MCF7 Imatinib
10
uM
LJP6
3
N13
72
hr
1235 4187 4126 1.0147 1.0168
MCF7 NVP-TAE684
0.04
uM
LJP6
1
K18
72
hr
1235 2917 3974 0.7340 0.6648