LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Tozasertib | 3.33 | uM | LJP5 | 1 | B14 | 72 | hr | 1235 | 1519 | 4119 | 0.3688 | 0.1263 |
| MCF7 | Tozasertib | 3.33 | uM | LJP5 | 2 | B14 | 72 | hr | 1235 | 1359 | 4356 | 0.3120 | 0.0539 |
| MCF7 | Tozasertib | 3.33 | uM | LJP5 | 3 | B14 | 72 | hr | 1235 | 1423 | 4326 | 0.3289 | 0.0813 |
| MCF7 | Tozasertib | 10 | uM | LJP5 | 1 | B13 | 72 | hr | 1235 | 1347 | 4119 | 0.3270 | 0.0510 |
| MCF7 | Tozasertib | 10 | uM | LJP5 | 2 | B13 | 72 | hr | 1235 | 1388 | 4356 | 0.3186 | 0.0662 |
| MCF7 | Tozasertib | 10 | uM | LJP5 | 3 | B13 | 72 | hr | 1235 | 1221 | 4326 | 0.2822 | -0.0065 |
| MCF7 | Imatinib | 0.04 | uM | LJP6 | 1 | N18 | 72 | hr | 1235 | 4264 | 3974 | 1.0729 | 1.0853 |
| MCF7 | Imatinib | 0.04 | uM | LJP6 | 2 | N18 | 72 | hr | 1235 | 4799 | 4070 | 1.1790 | 1.2009 |
| MCF7 | Imatinib | 0.04 | uM | LJP6 | 3 | N18 | 72 | hr | 1235 | 4380 | 4126 | 1.0615 | 1.0698 |
| MCF7 | Imatinib | 0.12 | uM | LJP6 | 1 | N17 | 72 | hr | 1235 | 4778 | 3974 | 1.2023 | 1.2310 |
| MCF7 | Imatinib | 0.12 | uM | LJP6 | 2 | N17 | 72 | hr | 1235 | 4039 | 4070 | 0.9923 | 0.9910 |
| MCF7 | Imatinib | 0.12 | uM | LJP6 | 3 | N17 | 72 | hr | 1235 | 4572 | 4126 | 1.1080 | 1.1214 |
| MCF7 | Imatinib | 0.37 | uM | LJP6 | 1 | N16 | 72 | hr | 1235 | 4993 | 3974 | 1.2564 | 1.2900 |
| MCF7 | Imatinib | 0.37 | uM | LJP6 | 2 | N16 | 72 | hr | 1235 | 4092 | 4070 | 1.0053 | 1.0062 |
| MCF7 | Imatinib | 0.37 | uM | LJP6 | 3 | N16 | 72 | hr | 1235 | 4804 | 4126 | 1.1642 | 1.1826 |
| MCF7 | Imatinib | 1.11 | uM | LJP6 | 1 | N15 | 72 | hr | 1235 | 4352 | 3974 | 1.0951 | 1.1107 |
| MCF7 | Imatinib | 1.11 | uM | LJP6 | 2 | N15 | 72 | hr | 1235 | 4165 | 4070 | 1.0233 | 1.0269 |
| MCF7 | Imatinib | 1.11 | uM | LJP6 | 3 | N15 | 72 | hr | 1235 | 4776 | 4126 | 1.1574 | 1.1753 |
| MCF7 | Imatinib | 3.33 | uM | LJP6 | 1 | N14 | 72 | hr | 1235 | 4581 | 3974 | 1.1527 | 1.1759 |
| MCF7 | Imatinib | 3.33 | uM | LJP6 | 2 | N14 | 72 | hr | 1235 | 3934 | 4070 | 0.9665 | 0.9608 |
| MCF7 | Imatinib | 3.33 | uM | LJP6 | 3 | N14 | 72 | hr | 1235 | 4492 | 4126 | 1.0886 | 1.1000 |
| MCF7 | Imatinib | 10 | uM | LJP6 | 1 | N13 | 72 | hr | 1235 | 3924 | 3974 | 0.9874 | 0.9850 |
| MCF7 | Imatinib | 10 | uM | LJP6 | 2 | N13 | 72 | hr | 1235 | 3367 | 4070 | 0.8272 | 0.7912 |
| MCF7 | Imatinib | 10 | uM | LJP6 | 3 | N13 | 72 | hr | 1235 | 4187 | 4126 | 1.0147 | 1.0168 |
| MCF7 | NVP-TAE684 | 0.04 | uM | LJP6 | 1 | K18 | 72 | hr | 1235 | 2917 | 3974 | 0.7340 | 0.6648 |