LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 7 of 15: Mean cell count and mean growth rate across all replicates. - Dataset (ID:20243)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Relative Growth Rate Standard Error of the Mean for Relative Growth Rate
Hs 578T Alpelisib
0.12
uM
LJP5
0.9215 0.0037 0.8974 0.0005
BT-20 GSK 690693
0.04
uM
LJP5
0.8635 0.0030 0.8023 0.0005
MCF7 Trametinib
0.37
uM
LJP5
0.4985 0.0120 0.3042 0.0005
Hs 578T Vemurafenib
0.12
uM
LJP5
1.0435 0.0025 1.0567 0.0007
MCF 10A PD173074
0.12
uM
LJP6
1.0158 0.0007 1.0176 0.0012
MCF7 Buparlisib
10.0
uM
LJP5
0.1893 0.0202 -0.1248 0.0013
MDA-MB-231 OSI-027
0.37
uM
LJP6
0.8164 0.0024 0.7514 0.0013
Hs 578T GSK1059615
0.12
uM
LJP5
0.8833 0.0046 0.8475 0.0013
MCF 10A Linifanib
0.12
uM
LJP6
1.0632 0.0033 1.0699 0.0014
MCF 10A PD173074
0.04
uM
LJP6
1.0449 0.0028 1.0497 0.0015
MDA-MB-231 R406
0.04
uM
LJP6
0.9856 0.0015 0.9805 0.0018
MCF 10A CP724714
3.33
uM
LJP5
0.9686 0.0023 0.9652 0.0018
Hs 578T Sigma A6730
0.04
uM
LJP5
0.9840 0.0010 0.9789 0.0020
MCF 10A Torin1
10.0
uM
LJP6
0.1288 0.0297 0.0349 0.0021
MCF7 Radicicol
0.12
uM
LJP6
0.4203 0.0127 0.1956 0.0023
BT-20 Seliciclib
0.04
uM
LJP5
1.0355 0.0023 1.0514 0.0025
MDA-MB-231 Buparlisib
0.12
uM
LJP5
0.9865 0.0020 0.9818 0.0026
Hs 578T TWS119
0.12
uM
LJP5
0.9952 0.0017 0.9935 0.0026
MCF 10A Geldanamycin
0.12
uM
LJP5
0.0979 0.0281 0.0005 0.0026
Hs 578T PF562271
0.04
uM
LJP6
0.8864 0.0030 0.8514 0.0027
Hs 578T Canertinib
1.11
uM
LJP6
0.9323 0.0047 0.9117 0.0027
MCF 10A Imatinib
0.12
uM
LJP6
1.0082 0.0025 1.0092 0.0028
MCF7 Tozasertib
10.0
uM
LJP5
0.3005 0.0147 0.0293 0.0028
MCF 10A Imatinib
0.37
uM
LJP6
1.0011 0.0025 1.0011 0.0028
MDA-MB-231 AZD8055
0.37
uM
LJP6
0.3994 0.0061 0.1868 0.0029
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