LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 7 of 15: Mean cell count and mean growth rate across all replicates. - Dataset (ID:20243)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Relative Growth Rate Standard Error of the Mean for Relative Growth Rate
SK-BR-3 XMD16-144
0.12
uM
LJP5
0.3770 0.0006 -0.0386 0.0617
MCF 10A PD173074
0.12
uM
LJP6
1.0158 0.0007 1.0176 0.0012
MDA-MB-231 AZD8055
1.11
uM
LJP6
0.3861 0.0008 0.1686 0.0070
Hs 578T Sigma A6730
0.04
uM
LJP5
0.9840 0.0010 0.9789 0.0020
BT-20 PIK-93
10.0
uM
LJP5
0.3620 0.0012 0.0754 0.0195
Hs 578T SU11274
0.04
uM
LJP5
1.0331 0.0012 1.0434 0.0030
MCF7 Fedratinib
10.0
uM
LJP5
0.1538 0.0013 -0.1754 0.0261
Hs 578T Brivanib
3.33
uM
LJP5
0.9354 0.0014 0.9152 0.0045
MDA-MB-231 R406
0.04
uM
LJP6
0.9856 0.0015 0.9805 0.0018
Hs 578T Nintedanib
0.37
uM
LJP6
0.7308 0.0015 0.6468 0.0174
MCF 10A GW843682X
10.0
uM
LJP6
0.0646 0.0015 -0.0386 0.0355
Hs 578T TWS119
0.12
uM
LJP5
0.9952 0.0017 0.9935 0.0026
Hs 578T TGX221
0.04
uM
LJP5
0.9330 0.0017 0.9122 0.0037
MDA-MB-231 Buparlisib
0.12
uM
LJP5
0.9865 0.0020 0.9818 0.0026
SK-BR-3 GSK1904529A
3.33
uM
LJP6
1.0030 0.0022 1.0048 0.0034
BT-20 PD184352
1.11
uM
LJP5
1.0053 0.0022 1.0077 0.0031
SK-BR-3 XMD16-144
1.11
uM
LJP5
0.3908 0.0022 -0.0159 0.0637
MCF 10A CP724714
3.33
uM
LJP5
0.9686 0.0023 0.9652 0.0018
BT-20 Seliciclib
0.04
uM
LJP5
1.0355 0.0023 1.0514 0.0025
MCF7 PHA-793887
0.37
uM
LJP6
0.2973 0.0023 0.0238 0.0243
BT-20 PIK-93
0.04
uM
LJP5
1.0379 0.0023 1.0550 0.0042
SK-BR-3 Tozasertib
0.04
uM
LJP5
0.3212 0.0024 -0.1311 0.0646
MDA-MB-231 OSI-027
0.37
uM
LJP6
0.8164 0.0024 0.7514 0.0013
MDA-MB-231 Tozasertib
0.04
uM
LJP5
0.3021 0.0024 0.0548 0.0081
Hs 578T SU11274
0.37
uM
LJP5
0.9572 0.0025 0.9437 0.0050
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