LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | CP724714 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3699 | 4093 | 0.9039 | 0.8636 |
| MCF7 | CP466722 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3824 | 4093 | 0.9344 | 0.9068 |
| MCF7 | Crizotinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2163 | 4093 | 0.5285 | 0.3307 |
| MCF7 | Momelotinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2752 | 4093 | 0.6725 | 0.5351 |
| MCF7 | Dasatinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1495 | 4093 | 0.3654 | 0.0992 |
| MCF7 | Dasatinib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1591 | 4093 | 0.3887 | 0.1323 |
| MCF7 | Dovitinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2067 | 4093 | 0.5052 | 0.2976 |
| MCF7 | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3959 | 4093 | 0.9673 | 0.9535 |
| MCF7 | Erlotinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 4308 | 4093 | 1.0527 | 1.0748 |
| MCF7 | Foretinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1355 | 4093 | 0.3312 | 0.0507 |
| MCF7 | R406 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 3712 | 4093 | 0.9069 | 0.8679 |
| MCF7 | Pictilisib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1216 | 4093 | 0.2971 | 0.0022 |
| MCF7 | Gefitinib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 4054 | 4093 | 0.9905 | 0.9865 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1263 | 4093 | 0.3087 | 0.0187 |
| MCF7 | Geldanamycin | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1260 | 4093 | 0.3079 | 0.0176 |
| MCF7 | GSK1059615 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1448 | 4093 | 0.3539 | 0.0828 |
| MCF7 | GSK1059615 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1785 | 4093 | 0.4363 | 0.1998 |
| MCF7 | GSK1904529A | 1.11 | uM | LJP6 | 72 | hr | 1209 | 2046 | 4093 | 0.5000 | 0.2902 |
| MCF7 | Omipalisib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1102 | 4093 | 0.2692 | -0.0373 |
| MCF7 | GSK 690693 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1923 | 4093 | 0.4698 | 0.2474 |
| MCF7 | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1367 | 4093 | 0.3342 | 0.0548 |
| MCF7 | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1448 | 4093 | 0.3539 | 0.0829 |
| MCF7 | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 2215 | 4093 | 0.5412 | 0.3487 |
| MCF7 | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 3996 | 4093 | 0.9765 | 0.9666 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 1209 | 460 | 4093 | 0.1125 | -0.2598 |