LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | GW843682X | 10.0 | uM | LJP6 | 72 | hr | 1209 | 1812 | 4093 | 0.4428 | 0.2091 |
| MCF7 | HG-5-113-01 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 569 | 4093 | 0.1392 | -0.2219 |
| MCF7 | HG-5-88-01 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 958 | 4093 | 0.2342 | -0.0870 |
| MCF7 | Imatinib | 10.0 | uM | LJP6 | 72 | hr | 1209 | 3530 | 4093 | 0.8625 | 0.8049 |
| MCF7 | JNK-9L | 10.0 | uM | LJP6 | 72 | hr | 1209 | 233 | 4093 | 0.0570 | -0.3386 |
| MCF7 | JW-7-24-1 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 937 | 4093 | 0.2289 | -0.0945 |
| MCF7 | Lapatinib | 10.0 | uM | LJP6 | 72 | hr | 1209 | 1584 | 4093 | 0.3872 | 0.1301 |
| MCF7 | LDN-193189 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 502 | 4093 | 0.1227 | -0.2453 |
| MCF7 | Linifanib | 10.0 | uM | LJP6 | 72 | hr | 1209 | 1152 | 4093 | 0.2816 | -0.0197 |
| MCF7 | Linsitinib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1647 | 4093 | 0.4026 | 0.1519 |
| MCF7 | Mitoxantrone | 10.0 | uM | LJP5 | 72 | hr | 1209 | 89 | 4093 | 0.0219 | -0.3884 |
| MCF7 | Mitoxantrone | 10.0 | uM | LJP6 | 72 | hr | 1209 | 70 | 4093 | 0.0171 | -0.3952 |
| MCF7 | MK2206 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 1071 | 4093 | 0.2617 | -0.0481 |
| MCF7 | Neratinib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1377 | 4093 | 0.3364 | 0.0581 |
| MCF7 | Nilotinib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 957 | 4093 | 0.2340 | -0.0874 |
| MCF7 | Nintedanib | 10.0 | uM | LJP6 | 72 | hr | 1209 | 1386 | 4093 | 0.3387 | 0.0613 |
| MCF7 | NU7441 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1259 | 4093 | 0.3076 | 0.0171 |
| MCF7 | Dactolisib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1240 | 4093 | 0.3030 | 0.0106 |
| MCF7 | NVP-TAE684 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 508 | 4093 | 0.1243 | -0.2431 |
| MCF7 | Palbociclib | 10.0 | uM | LJP6 | 72 | hr | 1209 | 1820 | 4093 | 0.4447 | 0.2118 |
| MCF7 | PD0325901 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1625 | 4093 | 0.3971 | 0.1442 |
| MCF7 | PD0325901 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 1471 | 4093 | 0.3594 | 0.0907 |
| MCF7 | PD173074 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 2693 | 4093 | 0.6580 | 0.5146 |
| MCF7 | PD184352 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 1981 | 4093 | 0.4842 | 0.2678 |
| MCF7 | Pelitinib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 849 | 4093 | 0.2075 | -0.1249 |