LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | JW-7-24-1 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1633 | 4093 | 0.3990 | 0.1469 |
| MCF7 | Lapatinib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 3510 | 4093 | 0.8576 | 0.7978 |
| MCF7 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3535 | 4093 | 0.8638 | 0.8067 |
| MCF7 | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 3641 | 4093 | 0.8897 | 0.8434 |
| MCF7 | Linsitinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2053 | 4093 | 0.5018 | 0.2927 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 1209 | 691 | 4093 | 0.1689 | -0.1797 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 1209 | 694 | 4093 | 0.1696 | -0.1787 |
| MCF7 | MK2206 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1819 | 4093 | 0.4446 | 0.2116 |
| MCF7 | Neratinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1594 | 4093 | 0.3895 | 0.1333 |
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3988 | 4093 | 0.9744 | 0.9636 |
| MCF7 | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 2818 | 4093 | 0.6885 | 0.5578 |
| MCF7 | NU7441 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3487 | 4093 | 0.8521 | 0.7901 |
| MCF7 | Dactolisib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 980 | 4093 | 0.2396 | -0.0794 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 878 | 4093 | 0.2146 | -0.1149 |
| MCF7 | Palbociclib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1989 | 4093 | 0.4861 | 0.2706 |
| MCF7 | PD0325901 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2197 | 4093 | 0.5369 | 0.3426 |
| MCF7 | PD0325901 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 2208 | 4093 | 0.5395 | 0.3464 |
| MCF7 | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 4272 | 4093 | 1.0438 | 1.0622 |
| MCF7 | PD184352 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2764 | 4093 | 0.6755 | 0.5393 |
| MCF7 | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2812 | 4093 | 0.6871 | 0.5559 |
| MCF7 | PF431396 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1289 | 4093 | 0.3150 | 0.0277 |
| MCF7 | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1707 | 4093 | 0.4171 | 0.1726 |
| MCF7 | PF562271 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1775 | 4093 | 0.4337 | 0.1961 |
| MCF7 | PHA-665752 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 4055 | 4093 | 0.9907 | 0.9868 |
| MCF7 | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1079 | 4093 | 0.2637 | -0.0452 |