LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PI103 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1007 | 4093 | 0.2462 | -0.0700 |
| MCF7 | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 4132 | 4093 | 1.0095 | 1.0135 |
| MCF7 | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1567 | 4093 | 0.3829 | 0.1241 |
| MCF7 | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1028 | 4093 | 0.2512 | -0.0630 |
| MCF7 | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1393 | 4093 | 0.3403 | 0.0636 |
| MCF7 | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1436 | 4093 | 0.3510 | 0.0788 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3350 | 4093 | 0.8185 | 0.7423 |
| MCF7 | Ruxolitinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 4523 | 4093 | 1.1052 | 1.1494 |
| MCF7 | XL147 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 4323 | 4093 | 1.0563 | 1.0799 |
| MCF7 | Saracatinib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 2815 | 4093 | 0.6878 | 0.5569 |
| MCF7 | Selumetinib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 2517 | 4093 | 0.6151 | 0.4537 |
| MCF7 | Sirolimus | 1.11 | uM | LJP6 | 72 | hr | 1209 | 2181 | 4093 | 0.5330 | 0.3371 |
| MCF7 | Sorafenib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 3953 | 4093 | 0.9660 | 0.9517 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3609 | 4093 | 0.8818 | 0.8323 |
| MCF7 | Fedratinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2137 | 4093 | 0.5222 | 0.3218 |
| MCF7 | TGX221 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 4008 | 4093 | 0.9793 | 0.9706 |
| MCF7 | Torin1 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1216 | 4093 | 0.2972 | 0.0024 |
| MCF7 | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1031 | 4093 | 0.2519 | -0.0619 |
| MCF7 | Tozasertib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1441 | 4093 | 0.3522 | 0.0804 |
| MCF7 | Trametinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2203 | 4093 | 0.5384 | 0.3448 |
| MCF7 | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 4004 | 4093 | 0.9783 | 0.9691 |
| MCF7 | Vemurafenib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 4204 | 4093 | 1.0272 | 1.0386 |
| MCF7 | Withaferin A | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1364 | 4093 | 0.3333 | 0.0536 |
| MCF7 | Withaferin A | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1327 | 4093 | 0.3242 | 0.0407 |
| MCF7 | WYE-125132 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1292 | 4093 | 0.3158 | 0.0288 |