LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 TWS119
10.0
uM
LJP5
 72
hr
 1209 1097 4093 0.2682 -0.0388
MCF7 Vemurafenib
10.0
uM
LJP5
 72
hr
 1209 3596 4093 0.8787 0.8279
MCF7 Withaferin A
10.0
uM
LJP5
 72
hr
 1209 744 4093 0.1818 -0.1615
MCF7 Withaferin A
10.0
uM
LJP6
 72
hr
 1209 664 4093 0.1623 -0.1891
MCF7 WYE-125132
10.0
uM
LJP6
 72
hr
 1209 879 4093 0.2148 -0.1145
MCF7 WZ3105
10.0
uM
LJP5
 72
hr
 1209 687 4093 0.1679 -0.1811
MCF7 XMD11-50
10.0
uM
LJP6
 72
hr
 1209 1277 4093 0.3122 0.0236
MCF7 Y39983
10.0
uM
LJP6
 72
hr
 1209 642 4093 0.1569 -0.1967
MCF7 YM 201636
10.0
uM
LJP5
 72
hr
 1209 435 4093 0.1064 -0.2684
MCF7 ZSTK474
10.0
uM
LJP6
 72
hr
 1209 925 4093 0.2261 -0.0986
MDA-MB-231 Afatinib
0.04
uM
LJP6
 72
hr
 1235 4254 4513 0.9426 0.9209
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 72
hr
 1235 4511 4513 0.9994 0.9992
MDA-MB-231 Alvocidib
0.04
uM
LJP6
 72
hr
 1235 1086 4513 0.2406 -0.0458
MDA-MB-231 AT-7519
0.04
uM
LJP6
 72
hr
 1235 2660 4513 0.5893 0.4345
MDA-MB-231 AZD 5438
0.04
uM
LJP6
 72
hr
 1235 3409 4513 0.7553 0.6631
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 72
hr
 1235 4318 4513 0.9567 0.9403
MDA-MB-231 AZD7762
0.04
uM
LJP6
 72
hr
 1235 3180 4513 0.7045 0.5931
MDA-MB-231 AZD8055
0.04
uM
LJP6
 72
hr
 1235 2611 4513 0.5785 0.4195
MDA-MB-231 AZD8330
0.04
uM
LJP5
 72
hr
 1235 1407 4513 0.3119 0.0524
MDA-MB-231 Barasertib
0.04
uM
LJP5
 72
hr
 1235 1520 4513 0.3369 0.0869
MDA-MB-231 BI-2536
0.04
uM
LJP6
 72
hr
 1235 999 4513 0.2214 -0.0722
MDA-MB-231 BMS345541
0.04
uM
LJP6
 72
hr
 1235 4330 4513 0.9594 0.9441
MDA-MB-231 SNS-032
0.04
uM
LJP6
 72
hr
 1235 2289 4513 0.5073 0.3215
MDA-MB-231 GDC-0980
0.04
uM
LJP5
 72
hr
 1235 3197 4513 0.7085 0.5985
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 72
hr
 1235 4811 4513 1.0660 1.0909