LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1241 | 4093 | 0.3033 | 0.0110 |
| MCF7 | BMS345541 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 2502 | 4093 | 0.6114 | 0.4483 |
| MCF7 | SNS-032 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 720 | 4093 | 0.1759 | -0.1698 |
| MCF7 | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1026 | 4093 | 0.2507 | -0.0637 |
| MCF7 | NVP-AEW541 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2159 | 4093 | 0.5275 | 0.3293 |
| MCF7 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 4189 | 4093 | 1.0235 | 1.0334 |
| MCF7 | PIK-93 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2696 | 4093 | 0.6587 | 0.5155 |
| MCF7 | KIN001-043 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 3378 | 4093 | 0.8254 | 0.7522 |
| MCF7 | Alpelisib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1779 | 4093 | 0.4347 | 0.1976 |
| MCF7 | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1244 | 4093 | 0.3039 | 0.0119 |
| MCF7 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 631 | 4093 | 0.1543 | -0.2005 |
| MCF7 | OSI-027 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1612 | 4093 | 0.3939 | 0.1397 |
| MCF7 | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 1209 | 3420 | 4093 | 0.8356 | 0.7666 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 4174 | 4093 | 1.0199 | 1.0282 |
| MCF7 | WH-4-025 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2171 | 4093 | 0.5306 | 0.3337 |
| MCF7 | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1815 | 4093 | 0.4434 | 0.2100 |
| MCF7 | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1515 | 4093 | 0.3702 | 0.1061 |
| MCF7 | Brivanib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3997 | 4093 | 0.9766 | 0.9667 |
| MCF7 | Buparlisib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 977 | 4093 | 0.2389 | -0.0804 |
| MCF7 | BX-912 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 2139 | 4093 | 0.5226 | 0.3223 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 3126 | 4093 | 0.7638 | 0.6648 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1395 | 4093 | 0.3409 | 0.0644 |
| MCF7 | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 591 | 4093 | 0.1444 | -0.2145 |
| MCF7 | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 672 | 4093 | 0.1644 | -0.1862 |
| MCF7 | CHIR-99021 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 3242 | 4093 | 0.7922 | 0.7050 |