LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Radicicol
1.11
uM
LJP6
 72
hr
 658 779 3846 0.2025 0.0379
Hs 578T Seliciclib
1.11
uM
LJP5
 72
hr
 658 3525 3846 0.9165 0.8993
Hs 578T Ruxolitinib
1.11
uM
LJP5
 72
hr
 658 3717 3846 0.9665 0.9596
Hs 578T XL147
1.11
uM
LJP5
 72
hr
 658 3843 3846 0.9994 0.9992
Hs 578T Saracatinib
1.11
uM
LJP6
 72
hr
 658 2857 3846 0.7430 0.6899
Hs 578T Selumetinib
1.11
uM
LJP6
 72
hr
 658 1794 3846 0.4666 0.3565
Hs 578T Sirolimus
1.11
uM
LJP6
 72
hr
 658 2457 3846 0.6390 0.5645
Hs 578T Sorafenib
1.11
uM
LJP6
 72
hr
 658 3950 3846 1.0270 1.0326
Hs 578T SU11274
1.11
uM
LJP5
 72
hr
 658 3493 3846 0.9082 0.8892
Hs 578T Fedratinib
1.11
uM
LJP5
 72
hr
 658 2164 3846 0.5627 0.4725
Hs 578T TGX221
1.11
uM
LJP5
 72
hr
 658 3518 3846 0.9147 0.8971
Hs 578T Torin1
1.11
uM
LJP6
 72
hr
 658 866 3846 0.2253 0.0654
Hs 578T Torin2
1.11
uM
LJP5
 72
hr
 658 554 3846 0.1440 -0.0327
Hs 578T Tozasertib
1.11
uM
LJP5
 72
hr
 658 716 3846 0.1862 0.0181
Hs 578T Trametinib
1.11
uM
LJP5
 72
hr
 658 932 3846 0.2423 0.0859
Hs 578T TWS119
1.11
uM
LJP5
 72
hr
 658 3374 3846 0.8773 0.8520
Hs 578T Vemurafenib
1.11
uM
LJP5
 72
hr
 658 3708 3846 0.9643 0.9569
Hs 578T Withaferin A
1.11
uM
LJP5
 72
hr
 658 650 3846 0.1690 -0.0026
Hs 578T Withaferin A
1.11
uM
LJP6
 72
hr
 658 651 3846 0.1694 -0.0022
Hs 578T WYE-125132
1.11
uM
LJP6
 72
hr
 658 1163 3846 0.3024 0.1584
Hs 578T WZ3105
1.11
uM
LJP5
 72
hr
 658 506 3846 0.1316 -0.0477
Hs 578T XMD11-50
1.11
uM
LJP6
 72
hr
 658 2353 3846 0.6120 0.5318
Hs 578T Y39983
1.11
uM
LJP6
 72
hr
 658 2905 3846 0.7553 0.7048
Hs 578T YM 201636
1.11
uM
LJP5
 72
hr
 658 3211 3846 0.8350 0.8009
Hs 578T ZSTK474
1.11
uM
LJP6
 72
hr
 658 1928 3846 0.5015 0.3985