LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T WZ3105
10.0
uM
LJP5
 72
hr
 658 454 3846 0.1180 -0.0641
Hs 578T XMD11-50
10.0
uM
LJP6
 72
hr
 658 616 3846 0.1603 -0.0131
Hs 578T Y39983
10.0
uM
LJP6
 72
hr
 658 567 3846 0.1476 -0.0284
Hs 578T YM 201636
10.0
uM
LJP5
 72
hr
 658 821 3846 0.2135 0.0511
Hs 578T ZSTK474
10.0
uM
LJP6
 72
hr
 658 1120 3846 0.2912 0.1449
MCF 10A Afatinib
0.04
uM
LJP6
 72
hr
 962 1713 10605 0.1616 0.0779
MCF 10A Sigma A6730
0.04
uM
LJP5
 72
hr
 962 10574 10605 0.9971 0.9968
MCF 10A Alvocidib
0.04
uM
LJP6
 72
hr
 962 722 10605 0.0681 -0.0248
MCF 10A AT-7519
0.04
uM
LJP6
 72
hr
 962 9592 10605 0.9045 0.8950
MCF 10A AZD 5438
0.04
uM
LJP6
 72
hr
 962 9619 10605 0.9071 0.8978
MCF 10A AZD-6482
0.04
uM
LJP5
 72
hr
 962 10549 10605 0.9947 0.9942
MCF 10A AZD7762
0.04
uM
LJP6
 72
hr
 962 10030 10605 0.9458 0.9404
MCF 10A AZD8055
0.04
uM
LJP6
 72
hr
 962 3374 10605 0.3182 0.2502
MCF 10A AZD8330
0.04
uM
LJP5
 72
hr
 962 1546 10605 0.1458 0.0606
MCF 10A Barasertib
0.04
uM
LJP5
 72
hr
 962 1437 10605 0.1355 0.0492
MCF 10A BI-2536
0.04
uM
LJP6
 72
hr
 962 786 10605 0.0741 -0.0183
MCF 10A BMS345541
0.04
uM
LJP6
 72
hr
 962 10478 10605 0.9881 0.9869
MCF 10A SNS-032
0.04
uM
LJP6
 72
hr
 962 9838 10605 0.9277 0.9205
MCF 10A GDC-0980
0.04
uM
LJP5
 72
hr
 962 8572 10605 0.8083 0.7892
MCF 10A NVP-AEW541
0.04
uM
LJP5
 72
hr
 962 10506 10605 0.9907 0.9898
MCF 10A SB590885
0.04
uM
LJP5
 72
hr
 962 8969 10605 0.8458 0.8304
MCF 10A PIK-93
0.04
uM
LJP5
 72
hr
 962 10362 10605 0.9771 0.9748
MCF 10A KIN001-043
0.04
uM
LJP6
 72
hr
 962 9995 10605 0.9425 0.9367
MCF 10A Alpelisib
0.04
uM
LJP5
 72
hr
 962 10528 10605 0.9928 0.9921
MCF 10A Luminespib
0.04
uM
LJP5
 72
hr
 962 834 10605 0.0786 -0.0133