LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A SB590885
0.37
uM
LJP5
 72
hr
 962 9190 10605 0.8666 0.8533
MCF 10A PIK-93
0.37
uM
LJP5
 72
hr
 962 9823 10605 0.9263 0.9190
MCF 10A KIN001-043
0.37
uM
LJP6
 72
hr
 962 9883 10605 0.9320 0.9252
MCF 10A Alpelisib
0.37
uM
LJP5
 72
hr
 962 9803 10605 0.9244 0.9168
MCF 10A Luminespib
0.37
uM
LJP5
 72
hr
 962 826 10605 0.0780 -0.0141
MCF 10A A443654
0.37
uM
LJP6
 72
hr
 962 1706 10605 0.1609 0.0772
MCF 10A OSI-027
0.37
uM
LJP6
 72
hr
 962 2731 10605 0.2576 0.1835
MCF 10A XMD11-85h
0.37
uM
LJP6
 72
hr
 962 10650 10605 1.0042 1.0047
MCF 10A HG-6-64-01
0.37
uM
LJP6
 72
hr
 962 10342 10605 0.9752 0.9728
MCF 10A WH-4-025
0.37
uM
LJP5
 72
hr
 962 7835 10605 0.7388 0.7127
MCF 10A WZ-4-145
0.37
uM
LJP6
 72
hr
 962 9478 10605 0.8938 0.8832
MCF 10A XMD16-144
0.37
uM
LJP5
 72
hr
 962 1603 10605 0.1512 0.0665
MCF 10A Brivanib
0.37
uM
LJP5
 72
hr
 962 10111 10605 0.9535 0.9488
MCF 10A Buparlisib
0.37
uM
LJP5
 72
hr
 962 9430 10605 0.8893 0.8782
MCF 10A BX-912
0.37
uM
LJP5
 72
hr
 962 2387 10605 0.2251 0.1478
MCF 10A Canertinib
0.37
uM
LJP6
 72
hr
 962 3517 10605 0.3316 0.2649
MCF 10A Celastrol
0.37
uM
LJP6
 72
hr
 962 9824 10605 0.9264 0.9190
MCF 10A CGP60474
0.37
uM
LJP5
 72
hr
 962 263 10605 0.0249 -0.0724
MCF 10A CGP60474
0.37
uM
LJP6
 72
hr
 962 277 10605 0.0262 -0.0710
MCF 10A CHIR-99021
0.37
uM
LJP6
 72
hr
 962 11501 10605 1.0845 1.0930
MCF 10A CP724714
0.37
uM
LJP5
 72
hr
 962 10536 10605 0.9935 0.9929
MCF 10A CP466722
0.37
uM
LJP5
 72
hr
 962 10451 10605 0.9855 0.9841
MCF 10A Crizotinib
0.37
uM
LJP5
 72
hr
 962 9789 10605 0.9231 0.9154
MCF 10A Momelotinib
0.37
uM
LJP5
 72
hr
 962 8778 10605 0.8278 0.8106
MCF 10A Dasatinib
0.37
uM
LJP5
 72
hr
 962 3086 10605 0.2911 0.2203