LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Mitoxantrone
1.11
uM
LJP5
 72
hr
 658 276 3846 0.0718 -0.1199
Hs 578T Mitoxantrone
1.11
uM
LJP6
 72
hr
 658 287 3846 0.0746 -0.1164
Hs 578T MK2206
1.11
uM
LJP6
 72
hr
 658 2627 3846 0.6831 0.6177
Hs 578T Neratinib
1.11
uM
LJP5
 72
hr
 658 1178 3846 0.3063 0.1631
Hs 578T Nilotinib
1.11
uM
LJP5
 72
hr
 658 3961 3846 1.0300 1.0361
Hs 578T Nintedanib
1.11
uM
LJP6
 72
hr
 658 2320 3846 0.6033 0.5214
Hs 578T NU7441
1.11
uM
LJP5
 72
hr
 658 3136 3846 0.8154 0.7773
Hs 578T Dactolisib
1.11
uM
LJP5
 72
hr
 658 920 3846 0.2394 0.0823
Hs 578T NVP-TAE684
1.11
uM
LJP6
 72
hr
 658 1122 3846 0.2918 0.1456
Hs 578T Palbociclib
1.11
uM
LJP6
 72
hr
 658 1643 3846 0.4274 0.3091
Hs 578T PD0325901
1.11
uM
LJP5
 72
hr
 658 1092 3846 0.2839 0.1361
Hs 578T PD0325901
1.11
uM
LJP6
 72
hr
 658 1054 3846 0.2742 0.1244
Hs 578T PD173074
1.11
uM
LJP6
 72
hr
 658 3185 3846 0.8281 0.7926
Hs 578T PD184352
1.11
uM
LJP5
 72
hr
 658 2468 3846 0.6417 0.5677
Hs 578T Pelitinib
1.11
uM
LJP5
 72
hr
 658 3026 3846 0.7868 0.7427
Hs 578T PF431396
1.11
uM
LJP5
 72
hr
 658 1163 3846 0.3025 0.1585
Hs 578T PF477736
1.11
uM
LJP5
 72
hr
 658 574 3846 0.1492 -0.0264
Hs 578T PF562271
1.11
uM
LJP6
 72
hr
 658 2385 3846 0.6201 0.5417
Hs 578T PHA-665752
1.11
uM
LJP5
 72
hr
 658 3570 3846 0.9282 0.9134
Hs 578T PHA-793887
1.11
uM
LJP6
 72
hr
 658 576 3846 0.1499 -0.0256
Hs 578T PI103
1.11
uM
LJP6
 72
hr
 658 1309 3846 0.3404 0.2043
Hs 578T PLX-4720
1.11
uM
LJP5
 72
hr
 658 3899 3846 1.0139 1.0168
Hs 578T QL-X-138
1.11
uM
LJP6
 72
hr
 658 1799 3846 0.4679 0.3581
Hs 578T QL-XII-47
1.11
uM
LJP6
 72
hr
 658 976 3846 0.2538 0.0997
Hs 578T Radicicol
1.11
uM
LJP5
 72
hr
 658 905 3846 0.2354 0.0775