LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Nintedanib
0.12
uM
LJP6
 72
hr
 658 3394 3846 0.8825 0.8583
Hs 578T NU7441
0.12
uM
LJP5
 72
hr
 658 3583 3846 0.9317 0.9176
Hs 578T Dactolisib
0.12
uM
LJP5
 72
hr
 658 980 3846 0.2549 0.1011
Hs 578T NVP-TAE684
0.12
uM
LJP6
 72
hr
 658 2583 3846 0.6716 0.6038
Hs 578T Palbociclib
0.12
uM
LJP6
 72
hr
 658 2070 3846 0.5382 0.4429
Hs 578T PD0325901
0.12
uM
LJP5
 72
hr
 658 1727 3846 0.4491 0.3354
Hs 578T PD0325901
0.12
uM
LJP6
 72
hr
 658 1775 3846 0.4616 0.3504
Hs 578T PD173074
0.12
uM
LJP6
 72
hr
 658 3209 3846 0.8344 0.8003
Hs 578T PD184352
0.12
uM
LJP5
 72
hr
 658 2986 3846 0.7765 0.7304
Hs 578T Pelitinib
0.12
uM
LJP5
 72
hr
 658 3425 3846 0.8905 0.8679
Hs 578T PF431396
0.12
uM
LJP5
 72
hr
 658 2663 3846 0.6926 0.6291
Hs 578T PF477736
0.12
uM
LJP5
 72
hr
 658 2350 3846 0.6111 0.5308
Hs 578T PF562271
0.12
uM
LJP6
 72
hr
 658 3098 3846 0.8056 0.7654
Hs 578T PHA-665752
0.12
uM
LJP5
 72
hr
 658 3930 3846 1.0220 1.0265
Hs 578T PHA-793887
0.12
uM
LJP6
 72
hr
 658 1492 3846 0.3880 0.2617
Hs 578T PI103
0.12
uM
LJP6
 72
hr
 658 1774 3846 0.4614 0.3502
Hs 578T PLX-4720
0.12
uM
LJP5
 72
hr
 658 4140 3846 1.0766 1.0924
Hs 578T QL-X-138
0.12
uM
LJP6
 72
hr
 658 3031 3846 0.7882 0.7444
Hs 578T QL-XII-47
0.12
uM
LJP6
 72
hr
 658 2595 3846 0.6749 0.6078
Hs 578T Radicicol
0.12
uM
LJP5
 72
hr
 658 3143 3846 0.8174 0.7797
Hs 578T Radicicol
0.12
uM
LJP6
 72
hr
 658 3029 3846 0.7876 0.7437
Hs 578T Seliciclib
0.12
uM
LJP5
 72
hr
 658 3900 3846 1.0141 1.0170
Hs 578T Ruxolitinib
0.12
uM
LJP5
 72
hr
 658 3642 3846 0.9471 0.9362
Hs 578T XL147
0.12
uM
LJP5
 72
hr
 658 3947 3846 1.0262 1.0316
Hs 578T Saracatinib
0.12
uM
LJP6
 72
hr
 658 3378 3846 0.8784 0.8533