LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A PF431396
0.12
uM
LJP5
 72
hr
 962 3745 10605 0.3532 0.2887
MCF 10A PF477736
0.12
uM
LJP5
 72
hr
 962 8621 10605 0.8129 0.7943
MCF 10A PF562271
0.12
uM
LJP6
 72
hr
 962 7356 10605 0.6936 0.6631
MCF 10A PHA-665752
0.12
uM
LJP5
 72
hr
 962 10179 10605 0.9598 0.9558
MCF 10A PHA-793887
0.12
uM
LJP6
 72
hr
 962 1859 10605 0.1753 0.0930
MCF 10A PI103
0.12
uM
LJP6
 72
hr
 962 5674 10605 0.5350 0.4886
MCF 10A PLX-4720
0.12
uM
LJP5
 72
hr
 962 9619 10605 0.9070 0.8977
MCF 10A QL-X-138
0.12
uM
LJP6
 72
hr
 962 10435 10605 0.9840 0.9824
MCF 10A QL-XII-47
0.12
uM
LJP6
 72
hr
 962 9610 10605 0.9062 0.8968
MCF 10A Radicicol
0.12
uM
LJP5
 72
hr
 962 6589 10605 0.6214 0.5836
MCF 10A Radicicol
0.12
uM
LJP6
 72
hr
 962 6550 10605 0.6177 0.5795
MCF 10A Seliciclib
0.12
uM
LJP5
 72
hr
 962 10036 10605 0.9464 0.9411
MCF 10A Ruxolitinib
0.12
uM
LJP5
 72
hr
 962 10299 10605 0.9712 0.9683
MCF 10A XL147
0.12
uM
LJP5
 72
hr
 962 10032 10605 0.9460 0.9406
MCF 10A Saracatinib
0.12
uM
LJP6
 72
hr
 962 10264 10605 0.9678 0.9646
MCF 10A Selumetinib
0.12
uM
LJP6
 72
hr
 962 3938 10605 0.3713 0.3086
MCF 10A Sirolimus
0.12
uM
LJP6
 72
hr
 962 9527 10605 0.8984 0.8883
MCF 10A Sorafenib
0.12
uM
LJP6
 72
hr
 962 9665 10605 0.9114 0.9025
MCF 10A SU11274
0.12
uM
LJP5
 72
hr
 962 9686 10605 0.9133 0.9047
MCF 10A Fedratinib
0.12
uM
LJP5
 72
hr
 962 9510 10605 0.8968 0.8865
MCF 10A TGX221
0.12
uM
LJP5
 72
hr
 962 10564 10605 0.9961 0.9957
MCF 10A Torin1
0.12
uM
LJP6
 72
hr
 962 2496 10605 0.2354 0.1591
MCF 10A Torin2
0.12
uM
LJP5
 72
hr
 962 1535 10605 0.1447 0.0594
MCF 10A Tozasertib
0.12
uM
LJP5
 72
hr
 962 1486 10605 0.1402 0.0544
MCF 10A Trametinib
0.12
uM
LJP5
 72
hr
 962 1803 10605 0.1700 0.0872