LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T JW-7-24-1
10.0
uM
LJP6
 72
hr
 658 280 3846 0.0730 -0.1184
Hs 578T Lapatinib
10.0
uM
LJP6
 72
hr
 658 1772 3846 0.4607 0.3494
Hs 578T LDN-193189
10.0
uM
LJP5
 72
hr
 658 212 3846 0.0551 -0.1400
Hs 578T Linifanib
10.0
uM
LJP6
 72
hr
 658 2041 3846 0.5307 0.4338
Hs 578T Linsitinib
10.0
uM
LJP5
 72
hr
 658 3511 3846 0.9130 0.8951
Hs 578T Mitoxantrone
10.0
uM
LJP5
 72
hr
 658 25 3846 0.0065 -0.1986
Hs 578T Mitoxantrone
10.0
uM
LJP6
 72
hr
 658 35 3846 0.0091 -0.1955
Hs 578T MK2206
10.0
uM
LJP6
 72
hr
 658 965 3846 0.2511 0.0965
Hs 578T Neratinib
10.0
uM
LJP5
 72
hr
 658 568 3846 0.1479 -0.0281
Hs 578T Nilotinib
10.0
uM
LJP5
 72
hr
 658 708 3846 0.1842 0.0157
Hs 578T Nintedanib
10.0
uM
LJP6
 72
hr
 658 684 3846 0.1778 0.0081
Hs 578T NU7441
10.0
uM
LJP5
 72
hr
 658 747 3846 0.1943 0.0280
Hs 578T Dactolisib
10.0
uM
LJP5
 72
hr
 658 971 3846 0.2525 0.0981
Hs 578T NVP-TAE684
10.0
uM
LJP6
 72
hr
 658 210 3846 0.0548 -0.1404
Hs 578T Palbociclib
10.0
uM
LJP6
 72
hr
 658 1295 3846 0.3367 0.1998
Hs 578T PD0325901
10.0
uM
LJP5
 72
hr
 658 787 3846 0.2046 0.0404
Hs 578T PD0325901
10.0
uM
LJP6
 72
hr
 658 715 3846 0.1859 0.0178
Hs 578T PD173074
10.0
uM
LJP6
 72
hr
 658 897 3846 0.2333 0.0750
Hs 578T PD184352
10.0
uM
LJP5
 72
hr
 658 1158 3846 0.3011 0.1568
Hs 578T Pelitinib
10.0
uM
LJP5
 72
hr
 658 448 3846 0.1167 -0.0657
Hs 578T PF431396
10.0
uM
LJP5
 72
hr
 658 570 3846 0.1482 -0.0277
Hs 578T PF477736
10.0
uM
LJP5
 72
hr
 658 449 3846 0.1169 -0.0654
Hs 578T PF562271
10.0
uM
LJP6
 72
hr
 658 568 3846 0.1479 -0.0281
Hs 578T PHA-665752
10.0
uM
LJP5
 72
hr
 658 53 3846 0.0140 -0.1896
Hs 578T PHA-793887
10.0
uM
LJP6
 72
hr
 658 457 3846 0.1190 -0.0629