LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T PI103
10.0
uM
LJP6
 72
hr
 658 909 3846 0.2364 0.0788
Hs 578T PLX-4720
10.0
uM
LJP5
 72
hr
 658 2868 3846 0.7457 0.6932
Hs 578T QL-X-138
10.0
uM
LJP6
 72
hr
 658 573 3846 0.1490 -0.0267
Hs 578T QL-XII-47
10.0
uM
LJP6
 72
hr
 658 578 3846 0.1503 -0.0252
Hs 578T Radicicol
10.0
uM
LJP5
 72
hr
 658 643 3846 0.1672 -0.0048
Hs 578T Radicicol
10.0
uM
LJP6
 72
hr
 658 609 3846 0.1585 -0.0152
Hs 578T Seliciclib
10.0
uM
LJP5
 72
hr
 658 2298 3846 0.5977 0.5146
Hs 578T Ruxolitinib
10.0
uM
LJP5
 72
hr
 658 2661 3846 0.6920 0.6285
Hs 578T XL147
10.0
uM
LJP5
 72
hr
 658 3179 3846 0.8266 0.7907
Hs 578T Saracatinib
10.0
uM
LJP6
 72
hr
 658 1574 3846 0.4094 0.2875
Hs 578T Selumetinib
10.0
uM
LJP6
 72
hr
 658 1216 3846 0.3163 0.1751
Hs 578T Sirolimus
10.0
uM
LJP6
 72
hr
 658 2466 3846 0.6412 0.5671
Hs 578T Sorafenib
10.0
uM
LJP6
 72
hr
 658 2751 3846 0.7154 0.6567
Hs 578T SU11274
10.0
uM
LJP5
 72
hr
 658 966 3846 0.2513 0.0968
Hs 578T Fedratinib
10.0
uM
LJP5
 72
hr
 658 373 3846 0.0971 -0.0894
Hs 578T TGX221
10.0
uM
LJP5
 72
hr
 658 2967 3846 0.7714 0.7242
Hs 578T Torin1
10.0
uM
LJP6
 72
hr
 658 459 3846 0.1195 -0.0623
Hs 578T Torin2
10.0
uM
LJP5
 72
hr
 658 447 3846 0.1164 -0.0660
Hs 578T Tozasertib
10.0
uM
LJP5
 72
hr
 658 786 3846 0.2044 0.0401
Hs 578T Trametinib
10.0
uM
LJP5
 72
hr
 658 946 3846 0.2461 0.0904
Hs 578T TWS119
10.0
uM
LJP5
 72
hr
 658 606 3846 0.1576 -0.0164
Hs 578T Vemurafenib
10.0
uM
LJP5
 72
hr
 658 1915 3846 0.4981 0.3945
Hs 578T Withaferin A
10.0
uM
LJP5
 72
hr
 658 397 3846 0.1032 -0.0819
Hs 578T Withaferin A
10.0
uM
LJP6
 72
hr
 658 338 3846 0.0881 -0.1002
Hs 578T WYE-125132
10.0
uM
LJP6
 72
hr
 658 1014 3846 0.2637 0.1117