LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A TWS119
0.12
uM
LJP5
 72
hr
 962 10401 10605 0.9808 0.9788
MCF 10A Vemurafenib
0.12
uM
LJP5
 72
hr
 962 10238 10605 0.9654 0.9620
MCF 10A Withaferin A
0.12
uM
LJP5
 72
hr
 962 11032 10605 1.0403 1.0443
MCF 10A Withaferin A
0.12
uM
LJP6
 72
hr
 962 10051 10605 0.9478 0.9426
MCF 10A WYE-125132
0.12
uM
LJP6
 72
hr
 962 1947 10605 0.1836 0.1022
MCF 10A WZ3105
0.12
uM
LJP5
 72
hr
 962 1505 10605 0.1420 0.0564
MCF 10A XMD11-50
0.12
uM
LJP6
 72
hr
 962 9197 10605 0.8672 0.8540
MCF 10A Y39983
0.12
uM
LJP6
 72
hr
 962 9910 10605 0.9345 0.9279
MCF 10A YM 201636
0.12
uM
LJP5
 72
hr
 962 10442 10605 0.9847 0.9832
MCF 10A ZSTK474
0.12
uM
LJP6
 72
hr
 962 9117 10605 0.8597 0.8457
MCF 10A Afatinib
0.37
uM
LJP6
 72
hr
 962 1405 10605 0.1325 0.0460
MCF 10A Sigma A6730
0.37
uM
LJP5
 72
hr
 962 10042 10605 0.9470 0.9417
MCF 10A Alvocidib
0.37
uM
LJP6
 72
hr
 962 200 10605 0.0189 -0.0790
MCF 10A AT-7519
0.37
uM
LJP6
 72
hr
 962 595 10605 0.0561 -0.0380
MCF 10A AZD 5438
0.37
uM
LJP6
 72
hr
 962 2408 10605 0.2271 0.1499
MCF 10A AZD-6482
0.37
uM
LJP5
 72
hr
 962 10138 10605 0.9560 0.9516
MCF 10A AZD7762
0.37
uM
LJP6
 72
hr
 962 6489 10605 0.6119 0.5732
MCF 10A AZD8055
0.37
uM
LJP6
 72
hr
 962 1649 10605 0.1555 0.0712
MCF 10A AZD8330
0.37
uM
LJP5
 72
hr
 962 1613 10605 0.1522 0.0676
MCF 10A Barasertib
0.37
uM
LJP5
 72
hr
 962 1401 10605 0.1321 0.0455
MCF 10A BI-2536
0.37
uM
LJP6
 72
hr
 962 1000 10605 0.0943 0.0039
MCF 10A BMS345541
0.37
uM
LJP6
 72
hr
 962 10337 10605 0.9748 0.9722
MCF 10A SNS-032
0.37
uM
LJP6
 72
hr
 962 452 10605 0.0426 -0.0529
MCF 10A GDC-0980
0.37
uM
LJP5
 72
hr
 962 1899 10605 0.1791 0.0972
MCF 10A NVP-AEW541
0.37
uM
LJP5
 72
hr
 962 10025 10605 0.9454 0.9399