LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T PF431396
0.37
uM
LJP5
 72
hr
 658 1815 3846 0.4719 0.3629
Hs 578T PF477736
0.37
uM
LJP5
 72
hr
 658 759 3846 0.1975 0.0318
Hs 578T PF562271
0.37
uM
LJP6
 72
hr
 658 2778 3846 0.7223 0.6650
Hs 578T PHA-665752
0.37
uM
LJP5
 72
hr
 658 3966 3846 1.0313 1.0378
Hs 578T PHA-793887
0.37
uM
LJP6
 72
hr
 658 891 3846 0.2317 0.0730
Hs 578T PI103
0.37
uM
LJP6
 72
hr
 658 1504 3846 0.3912 0.2655
Hs 578T PLX-4720
0.37
uM
LJP5
 72
hr
 658 4100 3846 1.0662 1.0798
Hs 578T QL-X-138
0.37
uM
LJP6
 72
hr
 658 2378 3846 0.6184 0.5396
Hs 578T QL-XII-47
0.37
uM
LJP6
 72
hr
 658 1963 3846 0.5104 0.4093
Hs 578T Radicicol
0.37
uM
LJP5
 72
hr
 658 1688 3846 0.4389 0.3230
Hs 578T Radicicol
0.37
uM
LJP6
 72
hr
 658 1309 3846 0.3403 0.2042
Hs 578T Seliciclib
0.37
uM
LJP5
 72
hr
 658 3790 3846 0.9854 0.9824
Hs 578T Ruxolitinib
0.37
uM
LJP5
 72
hr
 658 3683 3846 0.9576 0.9488
Hs 578T XL147
0.37
uM
LJP5
 72
hr
 658 3928 3846 1.0215 1.0259
Hs 578T Saracatinib
0.37
uM
LJP6
 72
hr
 658 3112 3846 0.8091 0.7697
Hs 578T Selumetinib
0.37
uM
LJP6
 72
hr
 658 1976 3846 0.5139 0.4135
Hs 578T Sirolimus
0.37
uM
LJP6
 72
hr
 658 2424 3846 0.6303 0.5540
Hs 578T Sorafenib
0.37
uM
LJP6
 72
hr
 658 4009 3846 1.0425 1.0513
Hs 578T SU11274
0.37
uM
LJP5
 72
hr
 658 3698 3846 0.9616 0.9536
Hs 578T Fedratinib
0.37
uM
LJP5
 72
hr
 658 3225 3846 0.8385 0.8052
Hs 578T TGX221
0.37
uM
LJP5
 72
hr
 658 3599 3846 0.9358 0.9225
Hs 578T Torin1
0.37
uM
LJP6
 72
hr
 658 1069 3846 0.2779 0.1289
Hs 578T Torin2
0.37
uM
LJP5
 72
hr
 658 522 3846 0.1359 -0.0425
Hs 578T Tozasertib
0.37
uM
LJP5
 72
hr
 658 789 3846 0.2051 0.0410
Hs 578T Trametinib
0.37
uM
LJP5
 72
hr
 658 891 3846 0.2317 0.0730