LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T GW843682X
0.37
uM
LJP6
 72
hr
 658 685 3846 0.1781 0.0084
Hs 578T HG-5-113-01
0.37
uM
LJP5
 72
hr
 658 2668 3846 0.6938 0.6306
Hs 578T HG-5-88-01
0.37
uM
LJP6
 72
hr
 658 3164 3846 0.8227 0.7861
Hs 578T Imatinib
0.37
uM
LJP6
 72
hr
 658 3634 3846 0.9449 0.9336
Hs 578T JNK-9L
0.37
uM
LJP6
 72
hr
 658 2984 3846 0.7759 0.7296
Hs 578T JW-7-24-1
0.37
uM
LJP6
 72
hr
 658 2601 3846 0.6764 0.6095
Hs 578T Lapatinib
0.37
uM
LJP6
 72
hr
 658 3714 3846 0.9658 0.9588
Hs 578T LDN-193189
0.37
uM
LJP5
 72
hr
 658 3304 3846 0.8591 0.8301
Hs 578T Linifanib
0.37
uM
LJP6
 72
hr
 658 3692 3846 0.9599 0.9517
Hs 578T Linsitinib
0.37
uM
LJP5
 72
hr
 658 3557 3846 0.9248 0.9093
Hs 578T Mitoxantrone
0.37
uM
LJP5
 72
hr
 658 491 3846 0.1278 -0.0523
Hs 578T Mitoxantrone
0.37
uM
LJP6
 72
hr
 658 535 3846 0.1392 -0.0385
Hs 578T MK2206
0.37
uM
LJP6
 72
hr
 658 2930 3846 0.7619 0.7127
Hs 578T Neratinib
0.37
uM
LJP5
 72
hr
 658 2043 3846 0.5312 0.4344
Hs 578T Nilotinib
0.37
uM
LJP5
 72
hr
 658 3952 3846 1.0276 1.0333
Hs 578T Nintedanib
0.37
uM
LJP6
 72
hr
 658 2819 3846 0.7331 0.6780
Hs 578T NU7441
0.37
uM
LJP5
 72
hr
 658 3618 3846 0.9409 0.9287
Hs 578T Dactolisib
0.37
uM
LJP5
 72
hr
 658 789 3846 0.2053 0.0412
Hs 578T NVP-TAE684
0.37
uM
LJP6
 72
hr
 658 1913 3846 0.4974 0.3936
Hs 578T Palbociclib
0.37
uM
LJP6
 72
hr
 658 1769 3846 0.4599 0.3484
Hs 578T PD0325901
0.37
uM
LJP5
 72
hr
 658 1357 3846 0.3530 0.2194
Hs 578T PD0325901
0.37
uM
LJP6
 72
hr
 658 1311 3846 0.3410 0.2050
Hs 578T PD173074
0.37
uM
LJP6
 72
hr
 658 3211 3846 0.8350 0.8010
Hs 578T PD184352
0.37
uM
LJP5
 72
hr
 658 2747 3846 0.7143 0.6553
Hs 578T Pelitinib
0.37
uM
LJP5
 72
hr
 658 3030 3846 0.7878 0.7440