LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T TGX221
3.33
uM
LJP5
 72
hr
 658 3510 3846 0.9126 0.8946
Hs 578T Torin1
3.33
uM
LJP6
 72
hr
 658 748 3846 0.1947 0.0284
Hs 578T Torin2
3.33
uM
LJP5
 72
hr
 658 533 3846 0.1386 -0.0393
Hs 578T Tozasertib
3.33
uM
LJP5
 72
hr
 658 791 3846 0.2058 0.0418
Hs 578T Trametinib
3.33
uM
LJP5
 72
hr
 658 905 3846 0.2353 0.0774
Hs 578T TWS119
3.33
uM
LJP5
 72
hr
 658 2381 3846 0.6192 0.5405
Hs 578T Vemurafenib
3.33
uM
LJP5
 72
hr
 658 3040 3846 0.7905 0.7472
Hs 578T Withaferin A
3.33
uM
LJP5
 72
hr
 658 581 3846 0.1512 -0.0241
Hs 578T Withaferin A
3.33
uM
LJP6
 72
hr
 658 583 3846 0.1516 -0.0236
Hs 578T WYE-125132
3.33
uM
LJP6
 72
hr
 658 1129 3846 0.2936 0.1478
Hs 578T WZ3105
3.33
uM
LJP5
 72
hr
 658 469 3846 0.1221 -0.0591
Hs 578T XMD11-50
3.33
uM
LJP6
 72
hr
 658 1683 3846 0.4377 0.3216
Hs 578T Y39983
3.33
uM
LJP6
 72
hr
 658 2439 3846 0.6343 0.5588
Hs 578T YM 201636
3.33
uM
LJP5
 72
hr
 658 2502 3846 0.6505 0.5784
Hs 578T ZSTK474
3.33
uM
LJP6
 72
hr
 658 1511 3846 0.3930 0.2676
Hs 578T Afatinib
10.0
uM
LJP6
 72
hr
 658 457 3846 0.1188 -0.0631
Hs 578T Sigma A6730
10.0
uM
LJP5
 72
hr
 658 1776 3846 0.4619 0.3507
Hs 578T Alvocidib
10.0
uM
LJP6
 72
hr
 658 384 3846 0.1000 -0.0858
Hs 578T AT-7519
10.0
uM
LJP6
 72
hr
 658 304 3846 0.0792 -0.1109
Hs 578T AZD 5438
10.0
uM
LJP6
 72
hr
 658 383 3846 0.0997 -0.0862
Hs 578T AZD-6482
10.0
uM
LJP5
 72
hr
 658 1861 3846 0.4840 0.3775
Hs 578T AZD7762
10.0
uM
LJP6
 72
hr
 658 203 3846 0.0530 -0.1426
Hs 578T AZD8055
10.0
uM
LJP6
 72
hr
 658 103 3846 0.0270 -0.1739
Hs 578T AZD8330
10.0
uM
LJP5
 72
hr
 658 1027 3846 0.2671 0.1158
Hs 578T Barasertib
10.0
uM
LJP5
 72
hr
 658 938 3846 0.2440 0.0879