LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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Hs 578T | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 658 | 471 | 3846 | 0.1226 | -0.0585 |
Hs 578T | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 658 | 3909 | 3846 | 1.0164 | 1.0198 |
Hs 578T | SNS-032 | 0.04 | uM | LJP6 | 72 | hr | 658 | 2942 | 3846 | 0.7651 | 0.7166 |
Hs 578T | GDC-0980 | 0.04 | uM | LJP5 | 72 | hr | 658 | 2318 | 3846 | 0.6029 | 0.5209 |
Hs 578T | NVP-AEW541 | 0.04 | uM | LJP5 | 72 | hr | 658 | 3972 | 3846 | 1.0328 | 1.0396 |
Hs 578T | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 658 | 4370 | 3846 | 1.1363 | 1.1644 |
Hs 578T | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 658 | 4012 | 3846 | 1.0433 | 1.0522 |
Hs 578T | KIN001-043 | 0.04 | uM | LJP6 | 72 | hr | 658 | 3895 | 3846 | 1.0127 | 1.0153 |
Hs 578T | Alpelisib | 0.04 | uM | LJP5 | 72 | hr | 658 | 3835 | 3846 | 0.9971 | 0.9965 |
Hs 578T | Luminespib | 0.04 | uM | LJP5 | 72 | hr | 658 | 771 | 3846 | 0.2006 | 0.0355 |
Hs 578T | A443654 | 0.04 | uM | LJP6 | 72 | hr | 658 | 2140 | 3846 | 0.5566 | 0.4650 |
Hs 578T | OSI-027 | 0.04 | uM | LJP6 | 72 | hr | 658 | 3699 | 3846 | 0.9618 | 0.9539 |
Hs 578T | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 658 | 3506 | 3846 | 0.9116 | 0.8933 |
Hs 578T | HG-6-64-01 | 0.04 | uM | LJP6 | 72 | hr | 658 | 3284 | 3846 | 0.8540 | 0.8239 |
Hs 578T | WH-4-025 | 0.04 | uM | LJP5 | 72 | hr | 658 | 3294 | 3846 | 0.8565 | 0.8269 |
Hs 578T | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 658 | 2421 | 3846 | 0.6295 | 0.5530 |
Hs 578T | XMD16-144 | 0.04 | uM | LJP5 | 72 | hr | 658 | 797 | 3846 | 0.2074 | 0.0438 |
Hs 578T | Brivanib | 0.04 | uM | LJP5 | 72 | hr | 658 | 3799 | 3846 | 0.9878 | 0.9852 |
Hs 578T | Buparlisib | 0.04 | uM | LJP5 | 72 | hr | 658 | 3642 | 3846 | 0.9470 | 0.9361 |
Hs 578T | BX-912 | 0.04 | uM | LJP5 | 72 | hr | 658 | 3664 | 3846 | 0.9528 | 0.9431 |
Hs 578T | Canertinib | 0.04 | uM | LJP6 | 72 | hr | 658 | 3904 | 3846 | 1.0152 | 1.0184 |
Hs 578T | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 658 | 3892 | 3846 | 1.0119 | 1.0144 |
Hs 578T | CGP60474 | 0.04 | uM | LJP5 | 72 | hr | 658 | 2861 | 3846 | 0.7439 | 0.6910 |
Hs 578T | CGP60474 | 0.04 | uM | LJP6 | 72 | hr | 658 | 524 | 3846 | 0.1364 | -0.0419 |
Hs 578T | CHIR-99021 | 0.04 | uM | LJP6 | 72 | hr | 658 | 3568 | 3846 | 0.9279 | 0.9130 |