LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 TGX221
10.0
uM
LJP5
 72
hr
 1097 3970 3769 1.0534 1.0753
BT-20 Torin1
10.0
uM
LJP6
 72
hr
 1097 669 3769 0.1777 -0.1600
BT-20 Torin2
10.0
uM
LJP5
 72
hr
 1097 656 3769 0.1740 -0.1651
BT-20 Tozasertib
10.0
uM
LJP5
 72
hr
 1097 1273 3769 0.3377 0.0658
BT-20 Trametinib
10.0
uM
LJP5
 72
hr
 1097 2916 3769 0.7736 0.6806
BT-20 TWS119
10.0
uM
LJP5
 72
hr
 1097 1149 3769 0.3049 0.0195
BT-20 Vemurafenib
10.0
uM
LJP5
 72
hr
 1097 2430 3769 0.6448 0.4990
BT-20 Withaferin A
10.0
uM
LJP5
 72
hr
 1097 615 3769 0.1632 -0.1805
BT-20 Withaferin A
10.0
uM
LJP6
 72
hr
 1097 566 3769 0.1502 -0.1987
BT-20 WYE-125132
10.0
uM
LJP6
 72
hr
 1097 1009 3769 0.2679 -0.0328
BT-20 WZ3105
10.0
uM
LJP5
 72
hr
 1097 661 3769 0.1754 -0.1631
BT-20 XMD11-50
10.0
uM
LJP6
 72
hr
 1097 1274 3769 0.3380 0.0661
BT-20 Y39983
10.0
uM
LJP6
 72
hr
 1097 1520 3769 0.4032 0.1582
BT-20 YM 201636
10.0
uM
LJP5
 72
hr
 1097 1092 3769 0.2899 -0.0017
BT-20 ZSTK474
10.0
uM
LJP6
 72
hr
 1097 925 3769 0.2456 -0.0642
Hs 578T Afatinib
0.04
uM
LJP6
 72
hr
 658 3556 3846 0.9247 0.9092
Hs 578T Sigma A6730
0.04
uM
LJP5
 72
hr
 658 3785 3846 0.9842 0.9809
Hs 578T Alvocidib
0.04
uM
LJP6
 72
hr
 658 1085 3846 0.2823 0.1341
Hs 578T AT-7519
0.04
uM
LJP6
 72
hr
 658 2831 3846 0.7361 0.6816
Hs 578T AZD 5438
0.04
uM
LJP6
 72
hr
 658 3192 3846 0.8299 0.7948
Hs 578T AZD-6482
0.04
uM
LJP5
 72
hr
 658 3702 3846 0.9627 0.9550
Hs 578T AZD7762
0.04
uM
LJP6
 72
hr
 658 2131 3846 0.5541 0.4620
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 658 1200 3846 0.3120 0.1700
Hs 578T AZD8330
0.04
uM
LJP5
 72
hr
 658 1041 3846 0.2707 0.1201
Hs 578T Barasertib
0.04
uM
LJP5
 72
hr
 658 1259 3846 0.3275 0.1887