LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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BT-20 | PF431396 | 1.11 | uM | LJP5 | 72 | hr | 1097 | 1364 | 3769 | 0.3619 | 0.0999 |
BT-20 | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 1097 | 3713 | 3769 | 0.9851 | 0.9790 |
BT-20 | PF562271 | 1.11 | uM | LJP6 | 72 | hr | 1097 | 2178 | 3769 | 0.5779 | 0.4046 |
BT-20 | PHA-665752 | 1.11 | uM | LJP5 | 72 | hr | 1097 | 3722 | 3769 | 0.9875 | 0.9823 |
BT-20 | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 1097 | 1086 | 3769 | 0.2881 | -0.0042 |
BT-20 | PI103 | 1.11 | uM | LJP6 | 72 | hr | 1097 | 1035 | 3769 | 0.2746 | -0.0233 |
BT-20 | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 1097 | 2883 | 3769 | 0.7648 | 0.6683 |
BT-20 | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 1097 | 2023 | 3769 | 0.5369 | 0.3467 |
BT-20 | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 1097 | 849 | 3769 | 0.2252 | -0.0929 |
BT-20 | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 1097 | 1167 | 3769 | 0.3097 | 0.0262 |
BT-20 | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 1097 | 1214 | 3769 | 0.3221 | 0.0438 |
BT-20 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 1097 | 3081 | 3769 | 0.8175 | 0.7426 |
BT-20 | Ruxolitinib | 1.11 | uM | LJP5 | 72 | hr | 1097 | 4001 | 3769 | 1.0614 | 1.0866 |
BT-20 | XL147 | 1.11 | uM | LJP5 | 72 | hr | 1097 | 3959 | 3769 | 1.0503 | 1.0709 |
BT-20 | Saracatinib | 1.11 | uM | LJP6 | 72 | hr | 1097 | 2888 | 3769 | 0.7661 | 0.6701 |
BT-20 | Selumetinib | 1.11 | uM | LJP6 | 72 | hr | 1097 | 3556 | 3769 | 0.9434 | 0.9202 |
BT-20 | Sirolimus | 1.11 | uM | LJP6 | 72 | hr | 1097 | 2201 | 3769 | 0.5840 | 0.4132 |
BT-20 | Sorafenib | 1.11 | uM | LJP6 | 72 | hr | 1097 | 3091 | 3769 | 0.8201 | 0.7462 |
BT-20 | SU11274 | 1.11 | uM | LJP5 | 72 | hr | 1097 | 3539 | 3769 | 0.9389 | 0.9139 |
BT-20 | Fedratinib | 1.11 | uM | LJP5 | 72 | hr | 1097 | 3146 | 3769 | 0.8346 | 0.7667 |
BT-20 | TGX221 | 1.11 | uM | LJP5 | 72 | hr | 1097 | 4111 | 3769 | 1.0907 | 1.1279 |
BT-20 | Torin1 | 1.11 | uM | LJP6 | 72 | hr | 1097 | 923 | 3769 | 0.2450 | -0.0650 |
BT-20 | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 1097 | 644 | 3769 | 0.1708 | -0.1696 |
BT-20 | Tozasertib | 1.11 | uM | LJP5 | 72 | hr | 1097 | 1187 | 3769 | 0.3149 | 0.0336 |
BT-20 | Trametinib | 1.11 | uM | LJP5 | 72 | hr | 1097 | 2759 | 3769 | 0.7321 | 0.6221 |