LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | GSK1059615 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 354 | 3769 | 0.0941 | -0.2779 |
| BT-20 | GSK1059615 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 454 | 3769 | 0.1206 | -0.2405 |
| BT-20 | GSK1904529A | 10.0 | uM | LJP6 | 72 | hr | 1097 | 3785 | 3769 | 1.0043 | 1.0060 |
| BT-20 | Omipalisib | 10.0 | uM | LJP6 | 72 | hr | 1097 | 428 | 3769 | 0.1135 | -0.2504 |
| BT-20 | GSK 690693 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 1836 | 3769 | 0.4872 | 0.2767 |
| BT-20 | GW843682X | 10.0 | uM | LJP6 | 72 | hr | 1097 | 1622 | 3769 | 0.4305 | 0.1966 |
| BT-20 | HG-5-113-01 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 934 | 3769 | 0.2479 | -0.0610 |
| BT-20 | HG-5-88-01 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 1969 | 3769 | 0.5225 | 0.3265 |
| BT-20 | Imatinib | 10.0 | uM | LJP6 | 72 | hr | 1097 | 3442 | 3769 | 0.9133 | 0.8777 |
| BT-20 | JNK-9L | 10.0 | uM | LJP6 | 72 | hr | 1097 | 792 | 3769 | 0.2101 | -0.1142 |
| BT-20 | JW-7-24-1 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 707 | 3769 | 0.1877 | -0.1458 |
| BT-20 | Lapatinib | 10.0 | uM | LJP6 | 72 | hr | 1097 | 2487 | 3769 | 0.6599 | 0.5202 |
| BT-20 | LDN-193189 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 211 | 3769 | 0.0562 | -0.3314 |
| BT-20 | Linifanib | 10.0 | uM | LJP6 | 72 | hr | 1097 | 1687 | 3769 | 0.4477 | 0.2209 |
| BT-20 | Linsitinib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 3196 | 3769 | 0.8479 | 0.7854 |
| BT-20 | Mitoxantrone | 10.0 | uM | LJP5 | 72 | hr | 1097 | 158 | 3769 | 0.0419 | -0.3515 |
| BT-20 | Mitoxantrone | 10.0 | uM | LJP6 | 72 | hr | 1097 | 201 | 3769 | 0.0535 | -0.3351 |
| BT-20 | MK2206 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 742 | 3769 | 0.1970 | -0.1327 |
| BT-20 | Neratinib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 1416 | 3769 | 0.3757 | 0.1194 |
| BT-20 | Nilotinib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 1040 | 3769 | 0.2760 | -0.0213 |
| BT-20 | Nintedanib | 10.0 | uM | LJP6 | 72 | hr | 1097 | 1948 | 3769 | 0.5169 | 0.3185 |
| BT-20 | NU7441 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 1317 | 3769 | 0.3494 | 0.0822 |
| BT-20 | Dactolisib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 1422 | 3769 | 0.3774 | 0.1218 |
| BT-20 | NVP-TAE684 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 1020 | 3769 | 0.2708 | -0.0287 |
| BT-20 | Palbociclib | 10.0 | uM | LJP6 | 72 | hr | 1097 | 1520 | 3769 | 0.4032 | 0.1582 |