LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | WZ-4-145 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 1200 | 3769 | 0.3185 | 0.0387 |
| BT-20 | XMD16-144 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 1051 | 3769 | 0.2789 | -0.0172 |
| BT-20 | Brivanib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 3290 | 3769 | 0.8728 | 0.8206 |
| BT-20 | Buparlisib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 621 | 3769 | 0.1648 | -0.1781 |
| BT-20 | BX-912 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 2291 | 3769 | 0.6079 | 0.4470 |
| BT-20 | Canertinib | 10.0 | uM | LJP6 | 72 | hr | 1097 | 760 | 3769 | 0.2017 | -0.1261 |
| BT-20 | Celastrol | 10.0 | uM | LJP6 | 72 | hr | 1097 | 333 | 3769 | 0.0883 | -0.2860 |
| BT-20 | CGP60474 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 509 | 3769 | 0.1351 | -0.2200 |
| BT-20 | CGP60474 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 427 | 3769 | 0.1135 | -0.2506 |
| BT-20 | CHIR-99021 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 2811 | 3769 | 0.7458 | 0.6414 |
| BT-20 | CP724714 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 2233 | 3769 | 0.5926 | 0.4253 |
| BT-20 | CP466722 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 2013 | 3769 | 0.5340 | 0.3427 |
| BT-20 | Crizotinib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 1085 | 3769 | 0.2879 | -0.0045 |
| BT-20 | Momelotinib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 1062 | 3769 | 0.2818 | -0.0131 |
| BT-20 | Dasatinib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 1098 | 3769 | 0.2914 | 0.0004 |
| BT-20 | Dasatinib | 10.0 | uM | LJP6 | 72 | hr | 1097 | 790 | 3769 | 0.2097 | -0.1149 |
| BT-20 | Dovitinib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 1357 | 3769 | 0.3601 | 0.0973 |
| BT-20 | Enzastaurin | 10.0 | uM | LJP5 | 72 | hr | 1097 | 4311 | 3769 | 1.1437 | 1.2027 |
| BT-20 | Erlotinib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 2595 | 3769 | 0.6884 | 0.5605 |
| BT-20 | Foretinib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 976 | 3769 | 0.2590 | -0.0453 |
| BT-20 | R406 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 1650 | 3769 | 0.4377 | 0.2068 |
| BT-20 | Pictilisib | 10.0 | uM | LJP6 | 72 | hr | 1097 | 889 | 3769 | 0.2358 | -0.0779 |
| BT-20 | Gefitinib | 10.0 | uM | LJP6 | 72 | hr | 1097 | 2640 | 3769 | 0.7004 | 0.5774 |
| BT-20 | Geldanamycin | 10.0 | uM | LJP5 | 72 | hr | 1097 | 629 | 3769 | 0.1669 | -0.1752 |
| BT-20 | Geldanamycin | 10.0 | uM | LJP6 | 72 | hr | 1097 | 604 | 3769 | 0.1604 | -0.1843 |