LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | Afatinib | 10.0 | uM | LJP6 | 72 | hr | 1097 | 816 | 3769 | 0.2166 | -0.1051 |
| BT-20 | Sigma A6730 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 1785 | 3769 | 0.4735 | 0.2574 |
| BT-20 | Alvocidib | 10.0 | uM | LJP6 | 72 | hr | 1097 | 586 | 3769 | 0.1555 | -0.1913 |
| BT-20 | AT-7519 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 529 | 3769 | 0.1404 | -0.2125 |
| BT-20 | AZD 5438 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 540 | 3769 | 0.1433 | -0.2085 |
| BT-20 | AZD-6482 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 792 | 3769 | 0.2103 | -0.1140 |
| BT-20 | AZD7762 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 456 | 3769 | 0.1211 | -0.2398 |
| BT-20 | AZD8055 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 119 | 3769 | 0.0317 | -0.3658 |
| BT-20 | AZD8330 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 3259 | 3769 | 0.8647 | 0.8091 |
| BT-20 | Barasertib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 1145 | 3769 | 0.3039 | 0.0181 |
| BT-20 | BI-2536 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 951 | 3769 | 0.2523 | -0.0547 |
| BT-20 | BMS345541 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 711 | 3769 | 0.1887 | -0.1444 |
| BT-20 | SNS-032 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 775 | 3769 | 0.2056 | -0.1206 |
| BT-20 | GDC-0980 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 754 | 3769 | 0.2001 | -0.1283 |
| BT-20 | NVP-AEW541 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 2984 | 3769 | 0.7916 | 0.7060 |
| BT-20 | SB590885 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 3380 | 3769 | 0.8968 | 0.8545 |
| BT-20 | PIK-93 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 1361 | 3769 | 0.3611 | 0.0988 |
| BT-20 | KIN001-043 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 1621 | 3769 | 0.4302 | 0.1962 |
| BT-20 | Alpelisib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 758 | 3769 | 0.2011 | -0.1270 |
| BT-20 | Luminespib | 10.0 | uM | LJP5 | 72 | hr | 1097 | 1241 | 3769 | 0.3293 | 0.0539 |
| BT-20 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 437 | 3769 | 0.1161 | -0.2468 |
| BT-20 | OSI-027 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 1275 | 3769 | 0.3384 | 0.0668 |
| BT-20 | XMD11-85h | 10.0 | uM | LJP6 | 72 | hr | 1097 | 2433 | 3769 | 0.6456 | 0.5001 |
| BT-20 | HG-6-64-01 | 10.0 | uM | LJP6 | 72 | hr | 1097 | 627 | 3769 | 0.1663 | -0.1760 |
| BT-20 | WH-4-025 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 733 | 3769 | 0.1945 | -0.1363 |