LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 Selumetinib
0.37
uM
LJP6
 72
hr
 1097 3537 3769 0.9385 0.9132
BT-20 Sirolimus
0.37
uM
LJP6
 72
hr
 1097 2186 3769 0.5800 0.4076
BT-20 Sorafenib
0.37
uM
LJP6
 72
hr
 1097 3050 3769 0.8091 0.7307
BT-20 SU11274
0.37
uM
LJP5
 72
hr
 1097 3913 3769 1.0381 1.0538
BT-20 Fedratinib
0.37
uM
LJP5
 72
hr
 1097 3539 3769 0.9388 0.9137
BT-20 TGX221
0.37
uM
LJP5
 72
hr
 1097 3823 3769 1.0143 1.0201
BT-20 Torin1
0.37
uM
LJP6
 72
hr
 1097 1006 3769 0.2669 -0.0341
BT-20 Torin2
0.37
uM
LJP5
 72
hr
 1097 771 3769 0.2046 -0.1220
BT-20 Tozasertib
0.37
uM
LJP5
 72
hr
 1097 1196 3769 0.3173 0.0370
BT-20 Trametinib
0.37
uM
LJP5
 72
hr
 1097 2861 3769 0.7591 0.6601
BT-20 TWS119
0.37
uM
LJP5
 72
hr
 1097 3565 3769 0.9458 0.9236
BT-20 Vemurafenib
0.37
uM
LJP5
 72
hr
 1097 3582 3769 0.9504 0.9301
BT-20 Withaferin A
0.37
uM
LJP5
 72
hr
 1097 2794 3769 0.7414 0.6352
BT-20 Withaferin A
0.37
uM
LJP6
 72
hr
 1097 2260 3769 0.5996 0.4352
BT-20 WYE-125132
0.37
uM
LJP6
 72
hr
 1097 1319 3769 0.3501 0.0832
BT-20 WZ3105
0.37
uM
LJP5
 72
hr
 1097 1143 3769 0.3032 0.0171
BT-20 XMD11-50
0.37
uM
LJP6
 72
hr
 1097 2621 3769 0.6953 0.5702
BT-20 Y39983
0.37
uM
LJP6
 72
hr
 1097 3468 3769 0.9202 0.8874
BT-20 YM 201636
0.37
uM
LJP5
 72
hr
 1097 3692 3769 0.9796 0.9712
BT-20 ZSTK474
0.37
uM
LJP6
 72
hr
 1097 1979 3769 0.5250 0.3300
BT-20 Afatinib
1.11
uM
LJP6
 72
hr
 1097 3152 3769 0.8364 0.7692
BT-20 Sigma A6730
1.11
uM
LJP5
 72
hr
 1097 3335 3769 0.8849 0.8376
BT-20 Alvocidib
1.11
uM
LJP6
 72
hr
 1097 612 3769 0.1624 -0.1816
BT-20 AT-7519
1.11
uM
LJP6
 72
hr
 1097 588 3769 0.1560 -0.1906
BT-20 AZD 5438
1.11
uM
LJP6
 72
hr
 1097 1022 3769 0.2712 -0.0280