LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 Radicicol
3.33
uM
LJP6
 72
hr
 1097 1007 3769 0.2673 -0.0335
BT-20 Seliciclib
3.33
uM
LJP5
 72
hr
 1097 2834 3769 0.7518 0.6499
BT-20 Ruxolitinib
3.33
uM
LJP5
 72
hr
 1097 3857 3769 1.0232 1.0327
BT-20 XL147
3.33
uM
LJP5
 72
hr
 1097 3318 3769 0.8803 0.8312
BT-20 Saracatinib
3.33
uM
LJP6
 72
hr
 1097 2338 3769 0.6203 0.4644
BT-20 Selumetinib
3.33
uM
LJP6
 72
hr
 1097 3360 3769 0.8915 0.8470
BT-20 Sirolimus
3.33
uM
LJP6
 72
hr
 1097 2310 3769 0.6128 0.4538
BT-20 Sorafenib
3.33
uM
LJP6
 72
hr
 1097 3110 3769 0.8252 0.7534
BT-20 SU11274
3.33
uM
LJP5
 72
hr
 1097 3273 3769 0.8685 0.8144
BT-20 Fedratinib
3.33
uM
LJP5
 72
hr
 1097 2597 3769 0.6891 0.5615
BT-20 TGX221
3.33
uM
LJP5
 72
hr
 1097 4159 3769 1.1033 1.1457
BT-20 Torin1
3.33
uM
LJP6
 72
hr
 1097 791 3769 0.2098 -0.1146
BT-20 Torin2
3.33
uM
LJP5
 72
hr
 1097 644 3769 0.1708 -0.1696
BT-20 Tozasertib
3.33
uM
LJP5
 72
hr
 1097 1215 3769 0.3224 0.0442
BT-20 Trametinib
3.33
uM
LJP5
 72
hr
 1097 2749 3769 0.7294 0.6184
BT-20 TWS119
3.33
uM
LJP5
 72
hr
 1097 2542 3769 0.6745 0.5409
BT-20 Vemurafenib
3.33
uM
LJP5
 72
hr
 1097 3335 3769 0.8848 0.8375
BT-20 Withaferin A
3.33
uM
LJP5
 72
hr
 1097 568 3769 0.1509 -0.1978
BT-20 Withaferin A
3.33
uM
LJP6
 72
hr
 1097 535 3769 0.1421 -0.2102
BT-20 WYE-125132
3.33
uM
LJP6
 72
hr
 1097 1166 3769 0.3095 0.0260
BT-20 WZ3105
3.33
uM
LJP5
 72
hr
 1097 721 3769 0.1913 -0.1408
BT-20 XMD11-50
3.33
uM
LJP6
 72
hr
 1097 2057 3769 0.5459 0.3594
BT-20 Y39983
3.33
uM
LJP6
 72
hr
 1097 2903 3769 0.7702 0.6759
BT-20 YM 201636
3.33
uM
LJP5
 72
hr
 1097 2295 3769 0.6088 0.4482
BT-20 ZSTK474
3.33
uM
LJP6
 72
hr
 1097 1050 3769 0.2786 -0.0176