LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | R406 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 4112 | 4223 | 0.9738 | 0.9608 |
| SK-BR-3 | Pictilisib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1864 | 4223 | 0.4415 | 0.1641 |
| SK-BR-3 | Gefitinib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3093 | 4223 | 0.7326 | 0.5997 |
| SK-BR-3 | Geldanamycin | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1489 | 4223 | 0.3526 | 0.0310 |
| SK-BR-3 | Geldanamycin | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1453 | 4223 | 0.3441 | 0.0182 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 2987 | 4223 | 0.7074 | 0.5620 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3031 | 4223 | 0.7179 | 0.5777 |
| SK-BR-3 | GSK1904529A | 0.37 | uM | LJP6 | 72 | hr | 1401 | 4046 | 4223 | 0.9582 | 0.9375 |
| SK-BR-3 | Omipalisib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1277 | 4223 | 0.3025 | -0.0439 |
| SK-BR-3 | GSK 690693 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 2938 | 4223 | 0.6958 | 0.5447 |
| SK-BR-3 | GW843682X | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1457 | 4223 | 0.3451 | 0.0198 |
| SK-BR-3 | HG-5-113-01 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3418 | 4223 | 0.8094 | 0.7148 |
| SK-BR-3 | HG-5-88-01 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3390 | 4223 | 0.8028 | 0.7049 |
| SK-BR-3 | Imatinib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 4499 | 4223 | 1.0653 | 1.0978 |
| SK-BR-3 | JNK-9L | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3306 | 4223 | 0.7830 | 0.6752 |
| SK-BR-3 | JW-7-24-1 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3069 | 4223 | 0.7267 | 0.5910 |
| SK-BR-3 | Lapatinib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1555 | 4223 | 0.3683 | 0.0545 |
| SK-BR-3 | LDN-193189 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4428 | 4223 | 1.0487 | 1.0729 |
| SK-BR-3 | Linifanib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 4681 | 4223 | 1.1084 | 1.1623 |
| SK-BR-3 | Linsitinib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3707 | 4223 | 0.8778 | 0.8171 |
| SK-BR-3 | Mitoxantrone | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1487 | 4223 | 0.3522 | 0.0304 |
| SK-BR-3 | Mitoxantrone | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1351 | 4223 | 0.3201 | -0.0177 |
| SK-BR-3 | MK2206 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 2683 | 4223 | 0.6355 | 0.4544 |
| SK-BR-3 | Neratinib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1408 | 4223 | 0.3335 | 0.0024 |
| SK-BR-3 | Nilotinib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4822 | 4223 | 1.1418 | 1.2123 |