LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP5 | 72 | hr | 1401 | 796 | 4223 | 0.1887 | -0.2144 |
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 1401 | 692 | 4223 | 0.1640 | -0.2512 |
| SK-BR-3 | MK2206 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 2185 | 4223 | 0.5174 | 0.2777 |
| SK-BR-3 | Neratinib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1415 | 4223 | 0.3352 | 0.0050 |
| SK-BR-3 | Nilotinib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 4741 | 4223 | 1.1226 | 1.1836 |
| SK-BR-3 | Nintedanib | 3.33 | uM | LJP6 | 72 | hr | 1401 | 3279 | 4223 | 0.7766 | 0.6656 |
| SK-BR-3 | NU7441 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3277 | 4223 | 0.7761 | 0.6648 |
| SK-BR-3 | Dactolisib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1560 | 4223 | 0.3696 | 0.0564 |
| SK-BR-3 | NVP-TAE684 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 2443 | 4223 | 0.5786 | 0.3692 |
| SK-BR-3 | Palbociclib | 3.33 | uM | LJP6 | 72 | hr | 1401 | 2794 | 4223 | 0.6618 | 0.4938 |
| SK-BR-3 | PD0325901 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 2728 | 4223 | 0.6461 | 0.4704 |
| SK-BR-3 | PD0325901 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 2620 | 4223 | 0.6205 | 0.4320 |
| SK-BR-3 | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 4313 | 4223 | 1.0214 | 1.0320 |
| SK-BR-3 | PD184352 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 4447 | 4223 | 1.0531 | 1.0795 |
| SK-BR-3 | Pelitinib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1398 | 4223 | 0.3312 | -0.0010 |
| SK-BR-3 | PF431396 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1521 | 4223 | 0.3603 | 0.0426 |
| SK-BR-3 | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1146 | 4223 | 0.2715 | -0.0903 |
| SK-BR-3 | PF562271 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1444 | 4223 | 0.3421 | 0.0153 |
| SK-BR-3 | PHA-665752 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3932 | 4223 | 0.9312 | 0.8970 |
| SK-BR-3 | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1311 | 4223 | 0.3105 | -0.0320 |
| SK-BR-3 | PI103 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1484 | 4223 | 0.3515 | 0.0293 |
| SK-BR-3 | PLX-4720 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3476 | 4223 | 0.8232 | 0.7353 |
| SK-BR-3 | QL-X-138 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1775 | 4223 | 0.4204 | 0.1325 |
| SK-BR-3 | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1266 | 4223 | 0.2999 | -0.0478 |
| SK-BR-3 | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1603 | 4223 | 0.3796 | 0.0714 |