LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Dasatinib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 436 | 4513 | 0.0967 | -0.2439 |
| MDA-MB-231 | Dovitinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 1548 | 4513 | 0.3430 | 0.0953 |
| MDA-MB-231 | Enzastaurin | 10.0 | uM | LJP5 | 72 | hr | 1235 | 5177 | 4513 | 1.1470 | 1.2025 |
| MDA-MB-231 | Erlotinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 3254 | 4513 | 0.7209 | 0.6157 |
| MDA-MB-231 | Foretinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 708 | 4513 | 0.1569 | -0.1610 |
| MDA-MB-231 | R406 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1315 | 4513 | 0.2913 | 0.0241 |
| MDA-MB-231 | Pictilisib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1869 | 4513 | 0.4141 | 0.1931 |
| MDA-MB-231 | Gefitinib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 3948 | 4513 | 0.8748 | 0.8275 |
| MDA-MB-231 | Geldanamycin | 10.0 | uM | LJP5 | 72 | hr | 1235 | 541 | 4513 | 0.1200 | -0.2118 |
| MDA-MB-231 | Geldanamycin | 10.0 | uM | LJP6 | 72 | hr | 1235 | 334 | 4513 | 0.0741 | -0.2751 |
| MDA-MB-231 | GSK1059615 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 518 | 4513 | 0.1148 | -0.2190 |
| MDA-MB-231 | GSK1059615 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 846 | 4513 | 0.1875 | -0.1189 |
| MDA-MB-231 | GSK1904529A | 10.0 | uM | LJP6 | 72 | hr | 1235 | 4220 | 4513 | 0.9350 | 0.9105 |
| MDA-MB-231 | Omipalisib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 723 | 4513 | 0.1602 | -0.1565 |
| MDA-MB-231 | GSK 690693 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 3718 | 4513 | 0.8238 | 0.7574 |
| MDA-MB-231 | GW843682X | 10.0 | uM | LJP6 | 72 | hr | 1235 | 1162 | 4513 | 0.2575 | -0.0225 |
| MDA-MB-231 | HG-5-113-01 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 750 | 4513 | 0.1662 | -0.1482 |
| MDA-MB-231 | HG-5-88-01 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 2525 | 4513 | 0.5594 | 0.3933 |
| MDA-MB-231 | Imatinib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 4164 | 4513 | 0.9225 | 0.8933 |
| MDA-MB-231 | JNK-9L | 10.0 | uM | LJP6 | 72 | hr | 1235 | 541 | 4513 | 0.1200 | -0.2118 |
| MDA-MB-231 | JW-7-24-1 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 632 | 4513 | 0.1401 | -0.1842 |
| MDA-MB-231 | Lapatinib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 2602 | 4513 | 0.5766 | 0.4169 |
| MDA-MB-231 | LDN-193189 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 522 | 4513 | 0.1157 | -0.2178 |
| MDA-MB-231 | Linifanib | 10.0 | uM | LJP6 | 72 | hr | 1235 | 969 | 4513 | 0.2148 | -0.0812 |
| MDA-MB-231 | Linsitinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 3356 | 4513 | 0.7437 | 0.6470 |