LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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Hs 578T | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 765 | 440 | 3124 | 0.1409 | -0.1376 |
Hs 578T | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 765 | 3082 | 3124 | 0.9864 | 0.9820 |
Hs 578T | SNS-032 | 0.04 | uM | LJP6 | 72 | hr | 765 | 2328 | 3124 | 0.7452 | 0.6626 |
Hs 578T | GDC-0980 | 0.04 | uM | LJP5 | 72 | hr | 765 | 2218 | 3124 | 0.7099 | 0.6158 |
Hs 578T | NVP-AEW541 | 0.04 | uM | LJP5 | 72 | hr | 765 | 3190 | 3124 | 1.0210 | 1.0277 |
Hs 578T | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 765 | 3790 | 3124 | 1.2132 | 1.2823 |
Hs 578T | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 765 | 3167 | 3124 | 1.0136 | 1.0180 |
Hs 578T | KIN001-043 | 0.04 | uM | LJP6 | 72 | hr | 765 | 3019 | 3124 | 0.9662 | 0.9553 |
Hs 578T | Alpelisib | 0.04 | uM | LJP5 | 72 | hr | 765 | 3014 | 3124 | 0.9646 | 0.9532 |
Hs 578T | Luminespib | 0.04 | uM | LJP5 | 72 | hr | 765 | 690 | 3124 | 0.2208 | -0.0318 |
Hs 578T | A443654 | 0.04 | uM | LJP6 | 72 | hr | 765 | 1997 | 3124 | 0.6394 | 0.5224 |
Hs 578T | OSI-027 | 0.04 | uM | LJP6 | 72 | hr | 765 | 2875 | 3124 | 0.9201 | 0.8942 |
Hs 578T | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 765 | 3051 | 3124 | 0.9765 | 0.9688 |
Hs 578T | HG-6-64-01 | 0.04 | uM | LJP6 | 72 | hr | 765 | 3471 | 3124 | 1.1111 | 1.1471 |
Hs 578T | WH-4-025 | 0.04 | uM | LJP5 | 72 | hr | 765 | 3084 | 3124 | 0.9870 | 0.9828 |
Hs 578T | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 765 | 2191 | 3124 | 0.7012 | 0.6044 |
Hs 578T | XMD16-144 | 0.04 | uM | LJP5 | 72 | hr | 765 | 1365 | 3124 | 0.4371 | 0.2546 |
Hs 578T | Brivanib | 0.04 | uM | LJP5 | 72 | hr | 765 | 3057 | 3124 | 0.9784 | 0.9714 |
Hs 578T | Buparlisib | 0.04 | uM | LJP5 | 72 | hr | 765 | 2958 | 3124 | 0.9467 | 0.9294 |
Hs 578T | BX-912 | 0.04 | uM | LJP5 | 72 | hr | 765 | 3105 | 3124 | 0.9938 | 0.9917 |
Hs 578T | Canertinib | 0.04 | uM | LJP6 | 72 | hr | 765 | 3023 | 3124 | 0.9676 | 0.9571 |
Hs 578T | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 765 | 3178 | 3124 | 1.0171 | 1.0227 |
Hs 578T | CGP60474 | 0.04 | uM | LJP5 | 72 | hr | 765 | 2650 | 3124 | 0.8481 | 0.7989 |
Hs 578T | CGP60474 | 0.04 | uM | LJP6 | 72 | hr | 765 | 346 | 3124 | 0.1110 | -0.1773 |
Hs 578T | CHIR-99021 | 0.04 | uM | LJP6 | 72 | hr | 765 | 3054 | 3124 | 0.9775 | 0.9703 |