LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 TGX221
10.0
uM
LJP5
 72
hr
 1334 4133 3970 1.0409 1.0616
BT-20 Torin1
10.0
uM
LJP6
 72
hr
 1334 803 3970 0.2023 -0.2016
BT-20 Torin2
10.0
uM
LJP5
 72
hr
 1334 667 3970 0.1681 -0.2530
BT-20 Tozasertib
10.0
uM
LJP5
 72
hr
 1334 1048 3970 0.2641 -0.1085
BT-20 Trametinib
10.0
uM
LJP5
 72
hr
 1334 3525 3970 0.8878 0.8310
BT-20 TWS119
10.0
uM
LJP5
 72
hr
 1334 1191 3970 0.2999 -0.0545
BT-20 Vemurafenib
10.0
uM
LJP5
 72
hr
 1334 2765 3970 0.6963 0.5426
BT-20 Withaferin A
10.0
uM
LJP5
 72
hr
 1334 865 3970 0.2179 -0.1780
BT-20 Withaferin A
10.0
uM
LJP6
 72
hr
 1334 771 3970 0.1942 -0.2138
BT-20 WYE-125132
10.0
uM
LJP6
 72
hr
 1334 1450 3970 0.3652 0.0437
BT-20 WZ3105
10.0
uM
LJP5
 72
hr
 1334 385 3970 0.0970 -0.3601
BT-20 XMD11-50
10.0
uM
LJP6
 72
hr
 1334 2234 3970 0.5626 0.3411
BT-20 Y39983
10.0
uM
LJP6
 72
hr
 1334 2476 3970 0.6237 0.4332
BT-20 YM 201636
10.0
uM
LJP5
 72
hr
 1334 1319 3970 0.3322 -0.0059
BT-20 ZSTK474
10.0
uM
LJP6
 72
hr
 1334 1209 3970 0.3045 -0.0477
Hs 578T Afatinib
0.04
uM
LJP6
 72
hr
 765 2933 3124 0.9387 0.9188
Hs 578T Sigma A6730
0.04
uM
LJP5
 72
hr
 765 3079 3124 0.9855 0.9808
Hs 578T Alvocidib
0.04
uM
LJP6
 72
hr
 765 1936 3124 0.6198 0.4966
Hs 578T AT-7519
0.04
uM
LJP6
 72
hr
 765 2849 3124 0.9120 0.8835
Hs 578T AZD 5438
0.04
uM
LJP6
 72
hr
 765 2937 3124 0.9400 0.9205
Hs 578T AZD-6482
0.04
uM
LJP5
 72
hr
 765 2821 3124 0.9029 0.8714
Hs 578T AZD7762
0.04
uM
LJP6
 72
hr
 765 1116 3124 0.3574 0.1490
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 765 1121 3124 0.3590 0.1511
Hs 578T AZD8330
0.04
uM
LJP5
 72
hr
 765 1146 3124 0.3670 0.1617
Hs 578T Barasertib
0.04
uM
LJP5
 72
hr
 765 1128 3124 0.3612 0.1541