LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T AZD-6482
0.37
uM
LJP5
 72
hr
 765 2629 3124 0.8416 0.7903
Hs 578T AZD7762
0.37
uM
LJP6
 72
hr
 765 565 3124 0.1809 -0.0846
Hs 578T AZD8055
0.37
uM
LJP6
 72
hr
 765 1078 3124 0.3451 0.1328
Hs 578T AZD8330
0.37
uM
LJP5
 72
hr
 765 1002 3124 0.3209 0.1007
Hs 578T Barasertib
0.37
uM
LJP5
 72
hr
 765 1089 3124 0.3486 0.1374
Hs 578T BI-2536
0.37
uM
LJP6
 72
hr
 765 468 3124 0.1498 -0.1259
Hs 578T BMS345541
0.37
uM
LJP6
 72
hr
 765 3024 3124 0.9680 0.9577
Hs 578T SNS-032
0.37
uM
LJP6
 72
hr
 765 422 3124 0.1351 -0.1454
Hs 578T GDC-0980
0.37
uM
LJP5
 72
hr
 765 1076 3124 0.3445 0.1319
Hs 578T NVP-AEW541
0.37
uM
LJP5
 72
hr
 765 3229 3124 1.0336 1.0446
Hs 578T SB590885
0.37
uM
LJP5
 72
hr
 765 3748 3124 1.1996 1.2644
Hs 578T PIK-93
0.37
uM
LJP5
 72
hr
 765 3122 3124 0.9993 0.9991
Hs 578T KIN001-043
0.37
uM
LJP6
 72
hr
 765 3132 3124 1.0025 1.0033
Hs 578T Alpelisib
0.37
uM
LJP5
 72
hr
 765 2660 3124 0.8515 0.8034
Hs 578T Luminespib
0.37
uM
LJP5
 72
hr
 765 664 3124 0.2127 -0.0425
Hs 578T A443654
0.37
uM
LJP6
 72
hr
 765 694 3124 0.2221 -0.0301
Hs 578T OSI-027
0.37
uM
LJP6
 72
hr
 765 2410 3124 0.7713 0.6972
Hs 578T XMD11-85h
0.37
uM
LJP6
 72
hr
 765 2984 3124 0.9550 0.9404
Hs 578T HG-6-64-01
0.37
uM
LJP6
 72
hr
 765 2937 3124 0.9402 0.9208
Hs 578T WH-4-025
0.37
uM
LJP5
 72
hr
 765 1499 3124 0.4799 0.3112
Hs 578T WZ-4-145
0.37
uM
LJP6
 72
hr
 765 1915 3124 0.6129 0.4874
Hs 578T XMD16-144
0.37
uM
LJP5
 72
hr
 765 845 3124 0.2707 0.0342
Hs 578T Brivanib
0.37
uM
LJP5
 72
hr
 765 3069 3124 0.9823 0.9766
Hs 578T Buparlisib
0.37
uM
LJP5
 72
hr
 765 2123 3124 0.6795 0.5755
Hs 578T BX-912
0.37
uM
LJP5
 72
hr
 765 2681 3124 0.8582 0.8122