LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
BT-20 | SB590885 | 3.33 | uM | LJP5 | 72 | hr | 1334 | 4161 | 3970 | 1.0479 | 1.0721 |
BT-20 | PIK-93 | 3.33 | uM | LJP5 | 72 | hr | 1334 | 3344 | 3970 | 0.8421 | 0.7622 |
BT-20 | KIN001-043 | 3.33 | uM | LJP6 | 72 | hr | 1334 | 3836 | 3970 | 0.9662 | 0.9491 |
BT-20 | Alpelisib | 3.33 | uM | LJP5 | 72 | hr | 1334 | 1664 | 3970 | 0.4192 | 0.1252 |
BT-20 | Luminespib | 3.33 | uM | LJP5 | 72 | hr | 1334 | 970 | 3970 | 0.2444 | -0.1382 |
BT-20 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1334 | 809 | 3970 | 0.2039 | -0.1992 |
BT-20 | OSI-027 | 3.33 | uM | LJP6 | 72 | hr | 1334 | 2279 | 3970 | 0.5740 | 0.3583 |
BT-20 | XMD11-85h | 3.33 | uM | LJP6 | 72 | hr | 1334 | 3786 | 3970 | 0.9535 | 0.9300 |
BT-20 | HG-6-64-01 | 3.33 | uM | LJP6 | 72 | hr | 1334 | 2156 | 3970 | 0.5430 | 0.3116 |
BT-20 | WH-4-025 | 3.33 | uM | LJP5 | 72 | hr | 1334 | 1841 | 3970 | 0.4637 | 0.1922 |
BT-20 | WZ-4-145 | 3.33 | uM | LJP6 | 72 | hr | 1334 | 3648 | 3970 | 0.9187 | 0.8775 |
BT-20 | XMD16-144 | 3.33 | uM | LJP5 | 72 | hr | 1334 | 1214 | 3970 | 0.3058 | -0.0457 |
BT-20 | Brivanib | 3.33 | uM | LJP5 | 72 | hr | 1334 | 3894 | 3970 | 0.9807 | 0.9710 |
BT-20 | Buparlisib | 3.33 | uM | LJP5 | 72 | hr | 1334 | 612 | 3970 | 0.1541 | -0.2741 |
BT-20 | BX-912 | 3.33 | uM | LJP5 | 72 | hr | 1334 | 3578 | 3970 | 0.9011 | 0.8511 |
BT-20 | Canertinib | 3.33 | uM | LJP6 | 72 | hr | 1334 | 3276 | 3970 | 0.8251 | 0.7365 |
BT-20 | Celastrol | 3.33 | uM | LJP6 | 72 | hr | 1334 | 1146 | 3970 | 0.2886 | -0.0716 |
BT-20 | CGP60474 | 3.33 | uM | LJP5 | 72 | hr | 1334 | 367 | 3970 | 0.0926 | -0.3668 |
BT-20 | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 1334 | 295 | 3970 | 0.0744 | -0.3943 |
BT-20 | CHIR-99021 | 3.33 | uM | LJP6 | 72 | hr | 1334 | 4087 | 3970 | 1.0293 | 1.0442 |
BT-20 | CP724714 | 3.33 | uM | LJP5 | 72 | hr | 1334 | 3473 | 3970 | 0.8746 | 0.8111 |
BT-20 | CP466722 | 3.33 | uM | LJP5 | 72 | hr | 1334 | 4026 | 3970 | 1.0140 | 1.0212 |
BT-20 | Crizotinib | 3.33 | uM | LJP5 | 72 | hr | 1334 | 2309 | 3970 | 0.5815 | 0.3696 |
BT-20 | Momelotinib | 3.33 | uM | LJP5 | 72 | hr | 1334 | 2983 | 3970 | 0.7514 | 0.6255 |
BT-20 | Dasatinib | 3.33 | uM | LJP5 | 72 | hr | 1334 | 1308 | 3970 | 0.3295 | -0.0100 |