LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 WZ3105
0.12
uM
LJP5
 72
hr
 1334 1118 3970 0.2816 -0.0822
BT-20 XMD11-50
0.12
uM
LJP6
 72
hr
 1334 3897 3970 0.9815 0.9721
BT-20 Y39983
0.12
uM
LJP6
 72
hr
 1334 4299 3970 1.0826 1.1245
BT-20 YM 201636
0.12
uM
LJP5
 72
hr
 1334 4143 3970 1.0435 1.0655
BT-20 ZSTK474
0.12
uM
LJP6
 72
hr
 1334 3917 3970 0.9866 0.9798
BT-20 Afatinib
0.37
uM
LJP6
 72
hr
 1334 3305 3970 0.8323 0.7474
BT-20 Sigma A6730
0.37
uM
LJP5
 72
hr
 1334 3862 3970 0.9727 0.9589
BT-20 Alvocidib
0.37
uM
LJP6
 72
hr
 1334 746 3970 0.1879 -0.2233
BT-20 AT-7519
0.37
uM
LJP6
 72
hr
 1334 3020 3970 0.7607 0.6395
BT-20 AZD 5438
0.37
uM
LJP6
 72
hr
 1334 2710 3970 0.6825 0.5217
BT-20 AZD-6482
0.37
uM
LJP5
 72
hr
 1334 3487 3970 0.8781 0.8164
BT-20 AZD7762
0.37
uM
LJP6
 72
hr
 1334 3122 3970 0.7862 0.6780
BT-20 AZD8055
0.37
uM
LJP6
 72
hr
 1334 1601 3970 0.4033 0.1012
BT-20 AZD8330
0.37
uM
LJP5
 72
hr
 1334 3272 3970 0.8240 0.7349
BT-20 Barasertib
0.37
uM
LJP5
 72
hr
 1334 1947 3970 0.4904 0.2324
BT-20 BI-2536
0.37
uM
LJP6
 72
hr
 1334 624 3970 0.1571 -0.2696
BT-20 BMS345541
0.37
uM
LJP6
 72
hr
 1334 3830 3970 0.9646 0.9467
BT-20 SNS-032
0.37
uM
LJP6
 72
hr
 1334 752 3970 0.1896 -0.2208
BT-20 GDC-0980
0.37
uM
LJP5
 72
hr
 1334 1192 3970 0.3002 -0.0541
BT-20 NVP-AEW541
0.37
uM
LJP5
 72
hr
 1334 4223 3970 1.0635 1.0956
BT-20 SB590885
0.37
uM
LJP5
 72
hr
 1334 4088 3970 1.0296 1.0445
BT-20 PIK-93
0.37
uM
LJP5
 72
hr
 1334 4274 3970 1.0764 1.1151
BT-20 KIN001-043
0.37
uM
LJP6
 72
hr
 1334 3439 3970 0.8661 0.7982
BT-20 Alpelisib
0.37
uM
LJP5
 72
hr
 1334 3247 3970 0.8177 0.7254
BT-20 Luminespib
0.37
uM
LJP5
 72
hr
 1334 949 3970 0.2390 -0.1463