LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 PI103
0.12
uM
LJP6
 72
hr
 1334 3794 3970 0.9555 0.9330
BT-20 PLX-4720
0.12
uM
LJP5
 72
hr
 1334 4044 3970 1.0185 1.0279
BT-20 QL-X-138
0.12
uM
LJP6
 72
hr
 1334 3182 3970 0.8013 0.7007
BT-20 QL-XII-47
0.12
uM
LJP6
 72
hr
 1334 3397 3970 0.8555 0.7823
BT-20 Radicicol
0.12
uM
LJP5
 72
hr
 1334 1952 3970 0.4916 0.2342
BT-20 Radicicol
0.12
uM
LJP6
 72
hr
 1334 2069 3970 0.5210 0.2786
BT-20 Seliciclib
0.12
uM
LJP5
 72
hr
 1334 4007 3970 1.0092 1.0138
BT-20 Ruxolitinib
0.12
uM
LJP5
 72
hr
 1334 3911 3970 0.9850 0.9774
BT-20 XL147
0.12
uM
LJP5
 72
hr
 1334 4014 3970 1.0109 1.0165
BT-20 Saracatinib
0.12
uM
LJP6
 72
hr
 1334 3738 3970 0.9414 0.9117
BT-20 Selumetinib
0.12
uM
LJP6
 72
hr
 1334 4277 3970 1.0772 1.1162
BT-20 Sirolimus
0.12
uM
LJP6
 72
hr
 1334 2412 3970 0.6075 0.4088
BT-20 Sorafenib
0.12
uM
LJP6
 72
hr
 1334 3764 3970 0.9481 0.9218
BT-20 SU11274
0.12
uM
LJP5
 72
hr
 1334 4234 3970 1.0664 1.1001
BT-20 Fedratinib
0.12
uM
LJP5
 72
hr
 1334 3935 3970 0.9910 0.9864
BT-20 TGX221
0.12
uM
LJP5
 72
hr
 1334 3991 3970 1.0051 1.0076
BT-20 Torin1
0.12
uM
LJP6
 72
hr
 1334 1692 3970 0.4262 0.1357
BT-20 Torin2
0.12
uM
LJP5
 72
hr
 1334 1185 3970 0.2984 -0.0568
BT-20 Tozasertib
0.12
uM
LJP5
 72
hr
 1334 1220 3970 0.3072 -0.0435
BT-20 Trametinib
0.12
uM
LJP5
 72
hr
 1334 3519 3970 0.8862 0.8286
BT-20 TWS119
0.12
uM
LJP5
 72
hr
 1334 4209 3970 1.0600 1.0903
BT-20 Vemurafenib
0.12
uM
LJP5
 72
hr
 1334 3808 3970 0.9591 0.9385
BT-20 Withaferin A
0.12
uM
LJP5
 72
hr
 1334 3607 3970 0.9084 0.8620
BT-20 Withaferin A
0.12
uM
LJP6
 72
hr
 1334 4046 3970 1.0190 1.0286
BT-20 WYE-125132
0.12
uM
LJP6
 72
hr
 1334 2175 3970 0.5477 0.3188