LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
SK-BR-3 GSK1059615
10.0
uM
LJP5
72
hr
1476 757 3694 0.2051 -0.3243
SK-BR-3 GSK1059615
10.0
uM
LJP6
72
hr
1476 843 3694 0.2283 -0.2857
SK-BR-3 GSK1904529A
10.0
uM
LJP6
72
hr
1476 3712 3694 1.0049 1.0081
SK-BR-3 Omipalisib
10.0
uM
LJP6
72
hr
1476 765 3694 0.2073 -0.3207
SK-BR-3 GSK 690693
10.0
uM
LJP5
72
hr
1476 3105 3694 0.8406 0.7345
SK-BR-3 GW843682X
10.0
uM
LJP6
72
hr
1476 2206 3694 0.5974 0.3292
SK-BR-3 HG-5-113-01
10.0
uM
LJP5
72
hr
1476 1296 3694 0.3509 -0.0814
SK-BR-3 HG-5-88-01
10.0
uM
LJP6
72
hr
1476 1696 3694 0.4591 0.0989
SK-BR-3 Imatinib
10.0
uM
LJP6
72
hr
1476 3656 3694 0.9898 0.9830
SK-BR-3 JNK-9L
10.0
uM
LJP6
72
hr
1476 1203 3694 0.3258 -0.1233
SK-BR-3 JW-7-24-1
10.0
uM
LJP6
72
hr
1476 1074 3694 0.2907 -0.1816
SK-BR-3 Lapatinib
10.0
uM
LJP6
72
hr
1476 1740 3694 0.4712 0.1190
SK-BR-3 LDN-193189
10.0
uM
LJP5
72
hr
1476 662 3694 0.1794 -0.3671
SK-BR-3 Linifanib
10.0
uM
LJP6
72
hr
1476 1846 3694 0.4999 0.1668
SK-BR-3 Linsitinib
10.0
uM
LJP5
72
hr
1476 2480 3694 0.6715 0.4528
SK-BR-3 Mitoxantrone
10.0
uM
LJP5
72
hr
1476 630 3694 0.1707 -0.3816
SK-BR-3 Mitoxantrone
10.0
uM
LJP6
72
hr
1476 544 3694 0.1474 -0.4204
SK-BR-3 MK2206
10.0
uM
LJP6
72
hr
1476 1342 3694 0.3634 -0.0606
SK-BR-3 Neratinib
10.0
uM
LJP5
72
hr
1476 1080 3694 0.2924 -0.1789
SK-BR-3 Nilotinib
10.0
uM
LJP5
72
hr
1476 2005 3694 0.5428 0.2383
SK-BR-3 Nintedanib
10.0
uM
LJP6
72
hr
1476 977 3694 0.2646 -0.2252
SK-BR-3 NU7441
10.0
uM
LJP5
72
hr
1476 1761 3694 0.4768 0.1284
SK-BR-3 Dactolisib
10.0
uM
LJP5
72
hr
1476 1602 3694 0.4339 0.0568
SK-BR-3 NVP-TAE684
10.0
uM
LJP6
72
hr
1476 965 3694 0.2613 -0.2306
SK-BR-3 Palbociclib
10.0
uM
LJP6
72
hr
1476 2583 3694 0.6993 0.4991