LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3495 | 3694 | 0.9461 | 0.9102 |
| SK-BR-3 | AZD7762 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1052 | 3694 | 0.2850 | -0.1912 |
| SK-BR-3 | AZD8055 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1313 | 3694 | 0.3556 | -0.0735 |
| SK-BR-3 | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3079 | 3694 | 0.8335 | 0.7226 |
| SK-BR-3 | Barasertib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1433 | 3694 | 0.3881 | -0.0194 |
| SK-BR-3 | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1546 | 3694 | 0.4187 | 0.0315 |
| SK-BR-3 | BMS345541 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2615 | 3694 | 0.7080 | 0.5135 |
| SK-BR-3 | SNS-032 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 905 | 3694 | 0.2452 | -0.2575 |
| SK-BR-3 | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1395 | 3694 | 0.3776 | -0.0369 |
| SK-BR-3 | NVP-AEW541 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3963 | 3694 | 1.0729 | 1.1214 |
| SK-BR-3 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 4251 | 3694 | 1.1508 | 1.2512 |
| SK-BR-3 | PIK-93 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3752 | 3694 | 1.0158 | 1.0263 |
| SK-BR-3 | KIN001-043 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 3008 | 3694 | 0.8145 | 0.6909 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 2575 | 3694 | 0.6973 | 0.4956 |
| SK-BR-3 | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1621 | 3694 | 0.4390 | 0.0654 |
| SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1195 | 3694 | 0.3237 | -0.1268 |
| SK-BR-3 | OSI-027 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1848 | 3694 | 0.5004 | 0.1678 |
| SK-BR-3 | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 1476 | 3011 | 3694 | 0.8151 | 0.6920 |
| SK-BR-3 | HG-6-64-01 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2797 | 3694 | 0.7572 | 0.5954 |
| SK-BR-3 | WH-4-025 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3096 | 3694 | 0.8383 | 0.7306 |
| SK-BR-3 | WZ-4-145 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1911 | 3694 | 0.5175 | 0.1962 |
| SK-BR-3 | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1444 | 3694 | 0.3909 | -0.0148 |
| SK-BR-3 | Brivanib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3169 | 3694 | 0.8581 | 0.7635 |
| SK-BR-3 | Buparlisib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1141 | 3694 | 0.3089 | -0.1514 |
| SK-BR-3 | BX-912 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1311 | 3694 | 0.3551 | -0.0744 |