LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A GSK1904529A
0.04
uM
LJP6
 72
hr
 513 3073 10401 0.2955 0.2589
MDA-MB-231 R406
0.04
uM
LJP6
 72
hr
 868 3428 3486 0.9834 0.9778
BT-20 LDN-193189
0.04
uM
LJP5
 72
hr
 1657 5401 5505 0.9811 0.9730
MCF 10A GW843682X
0.04
uM
LJP6
 72
hr
 513 9055 10401 0.8706 0.8639
MDA-MB-231 Geldanamycin
0.04
uM
LJP6
 72
hr
 868 1639 3486 0.4703 0.2947
MDA-MB-231 GSK1059615
0.04
uM
LJP5
 72
hr
 868 3825 3486 1.0972 1.1294
MCF 10A HG-5-88-01
0.04
uM
LJP6
 72
hr
 513 7496 10401 0.7207 0.7062
MDA-MB-231 Omipalisib
0.04
uM
LJP6
 72
hr
 868 2095 3486 0.6011 0.4688
MCF 10A HG-5-113-01
0.04
uM
LJP5
 72
hr
 513 9757 10401 0.9381 0.9349
MDA-MB-231 GW843682X
0.04
uM
LJP6
 72
hr
 868 2934 3486 0.8417 0.7892
BT-20 Linifanib
0.04
uM
LJP6
 72
hr
 1657 5888 5505 1.0694 1.0994
BT-20 Sigma A6730
0.04
uM
LJP5
 72
hr
 1657 4910 5505 0.8918 0.8452
BT-20 SB590885
0.04
uM
LJP5
 72
hr
 1657 5376 5505 0.9765 0.9663
Hs 578T Mitoxantrone
0.04
uM
LJP6
 72
hr
 929 1329 3228 0.4117 0.1739
BT-20 Celastrol
0.04
uM
LJP6
 72
hr
 1657 5828 5505 1.0587 1.0839
Hs 578T Mitoxantrone
0.04
uM
LJP5
 72
hr
 929 1292 3228 0.4003 0.1580
Hs 578T PD0325901
0.04
uM
LJP6
 72
hr
 929 1786 3228 0.5534 0.3728
Hs 578T Linsitinib
0.04
uM
LJP5
 72
hr
 929 3174 3228 0.9834 0.9766
BT-20 Linsitinib
0.04
uM
LJP5
 72
hr
 1657 4776 5505 0.8676 0.8106
Hs 578T Nilotinib
0.04
uM
LJP5
 72
hr
 929 3632 3228 1.1253 1.1760
BT-20 AT-7519
0.04
uM
LJP6
 72
hr
 1657 5115 5505 0.9291 0.8986
Hs 578T MK2206
0.04
uM
LJP6
 72
hr
 929 2927 3228 0.9067 0.8690
BT-20 AZD8055
0.04
uM
LJP6
 72
hr
 1657 2584 5505 0.4695 0.2409
MDA-MB-231 Linsitinib
0.04
uM
LJP5
 72
hr
 868 2600 3486 0.7460 0.6617
MDA-MB-231 Linifanib
0.04
uM
LJP6
 72
hr
 868 3905 3486 1.1201 1.1599