LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 LDN-193189
0.04
uM
LJP5
 72
hr
 1657 5401 5505 0.9811 0.9730
Hs 578T CP724714
0.04
uM
LJP5
 72
hr
 929 3174 3228 0.9835 0.9768
Hs 578T Crizotinib
0.04
uM
LJP5
 72
hr
 929 3151 3228 0.9761 0.9665
Hs 578T CP466722
0.04
uM
LJP5
 72
hr
 929 3355 3228 1.0394 1.0554
BT-20 Linifanib
0.04
uM
LJP6
 72
hr
 1657 5888 5505 1.0694 1.0994
BT-20 SB590885
0.04
uM
LJP5
 72
hr
 1657 5376 5505 0.9765 0.9663
BT-20 Celastrol
0.04
uM
LJP6
 72
hr
 1657 5828 5505 1.0587 1.0839
Hs 578T Alvocidib
0.04
uM
LJP6
 72
hr
 929 2245 3228 0.6956 0.5725
BT-20 Linsitinib
0.04
uM
LJP5
 72
hr
 1657 4776 5505 0.8676 0.8106
BT-20 AT-7519
0.04
uM
LJP6
 72
hr
 1657 5115 5505 0.9291 0.8986
BT-20 AZD8055
0.04
uM
LJP6
 72
hr
 1657 2584 5505 0.4695 0.2409
Hs 578T Afatinib
0.04
uM
LJP6
 72
hr
 929 3069 3228 0.9509 0.9311
BT-20 Mitoxantrone
0.04
uM
LJP5
 72
hr
 1657 2816 5505 0.5115 0.3011
Hs 578T AZD-6482
0.04
uM
LJP5
 72
hr
 929 3064 3228 0.9492 0.9286
BT-20 CGP60474
0.04
uM
LJP5
 72
hr
 1657 5524 5505 1.0034 1.0049
Hs 578T AT-7519
0.04
uM
LJP6
 72
hr
 929 3200 3228 0.9913 0.9878
BT-20 Mitoxantrone
0.04
uM
LJP6
 72
hr
 1657 2752 5505 0.4999 0.2845
Hs 578T AZD7762
0.04
uM
LJP6
 72
hr
 929 1764 3228 0.5466 0.3633
Hs 578T AZD8330
0.04
uM
LJP5
 72
hr
 929 1531 3228 0.4745 0.2621
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 929 1457 3228 0.4516 0.2299
BT-20 MK2206
0.04
uM
LJP6
 72
hr
 1657 5368 5505 0.9751 0.9643
BT-20 PIK-93
0.04
uM
LJP5
 72
hr
 1657 5721 5505 1.0392 1.0560
BT-20 CGP60474
0.04
uM
LJP6
 72
hr
 1657 1217 5505 0.2211 -0.1145
MCF 10A Foretinib
0.04
uM
LJP5
 72
hr
 513 11133 10401 1.0704 1.0741
MCF 10A Erlotinib
0.04
uM
LJP5
 72
hr
 513 9926 10401 0.9543 0.9520