LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Dasatinib
3.33
uM
LJP5
 72
hr
 929 1290 3228 0.3998 0.1572
Hs 578T Dasatinib
3.33
uM
LJP6
 72
hr
 929 1040 3228 0.3224 0.0485
Hs 578T Foretinib
3.33
uM
LJP5
 72
hr
 929 1491 3228 0.4620 0.2445
Hs 578T R406
3.33
uM
LJP6
 72
hr
 929 2188 3228 0.6779 0.5477
Hs 578T Gefitinib
3.33
uM
LJP6
 72
hr
 929 3184 3228 0.9866 0.9811
Hs 578T Geldanamycin
3.33
uM
LJP5
 72
hr
 929 1218 3228 0.3775 0.1259
Hs 578T GSK1059615
3.33
uM
LJP6
 72
hr
 929 1302 3228 0.4035 0.1624
Hs 578T GSK1904529A
3.33
uM
LJP6
 72
hr
 929 3087 3228 0.9565 0.9389
Hs 578T GSK 690693
3.33
uM
LJP5
 72
hr
 929 2298 3228 0.7119 0.5954
Hs 578T GW843682X
3.33
uM
LJP6
 72
hr
 929 847 3228 0.2624 -0.0358
Hs 578T Afatinib
0.04
uM
LJP6
 72
hr
 929 3069 3228 0.9509 0.9311
Hs 578T Sigma A6730
0.04
uM
LJP5
 72
hr
 929 3170 3228 0.9822 0.9750
Hs 578T AT-7519
0.04
uM
LJP6
 72
hr
 929 3200 3228 0.9913 0.9878
Hs 578T AZD 5438
0.04
uM
LJP6
 72
hr
 929 2947 3228 0.9129 0.8777
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 929 1457 3228 0.4516 0.2299
Hs 578T AZD8330
0.04
uM
LJP5
 72
hr
 929 1531 3228 0.4745 0.2621
Hs 578T BI-2536
0.04
uM
LJP6
 72
hr
 929 899 3228 0.2787 -0.0129
Hs 578T BMS345541
0.04
uM
LJP6
 72
hr
 929 3254 3228 1.0082 1.0116
Hs 578T SB590885
0.04
uM
LJP5
 72
hr
 929 3913 3228 1.2123 1.2981
Hs 578T PIK-93
0.04
uM
LJP5
 72
hr
 929 3293 3228 1.0203 1.0285
Hs 578T Alpelisib
0.04
uM
LJP5
 72
hr
 929 3166 3228 0.9808 0.9730
Hs 578T Luminespib
0.04
uM
LJP5
 72
hr
 929 1342 3228 0.4157 0.1796
Hs 578T XMD11-85h
0.04
uM
LJP6
 72
hr
 929 3182 3228 0.9857 0.9800
Hs 578T Linsitinib
3.33
uM
LJP5
 72
hr
 929 3132 3228 0.9702 0.9582
Hs 578T Linifanib
3.33
uM
LJP6
 72
hr
 929 3085 3228 0.9558 0.9379