LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Dasatinib
0.04
uM
LJP6
 72
hr
 513 1706 10401 0.1641 0.1207
MCF 10A Dasatinib
0.04
uM
LJP5
 72
hr
 513 4779 10401 0.4595 0.4314
MCF 10A Momelotinib
0.04
uM
LJP5
 72
hr
 513 8973 10401 0.8627 0.8556
MCF 10A Crizotinib
0.04
uM
LJP5
 72
hr
 513 9680 10401 0.9307 0.9271
MCF 10A CP466722
0.04
uM
LJP5
 72
hr
 513 10852 10401 1.0433 1.0456
MCF 10A CP724714
0.04
uM
LJP5
 72
hr
 513 10600 10401 1.0192 1.0202
MCF 10A CHIR-99021
0.04
uM
LJP6
 72
hr
 513 9979 10401 0.9594 0.9573
MCF 10A CGP60474
0.04
uM
LJP6
 72
hr
 513 542 10401 0.0522 0.0030
MCF 10A CGP60474
0.04
uM
LJP5
 72
hr
 513 4985 10401 0.4793 0.4523
MCF 10A Celastrol
0.04
uM
LJP6
 72
hr
 513 11579 10401 1.1132 1.1191
MCF 10A Canertinib
0.04
uM
LJP6
 72
hr
 513 2411 10401 0.2318 0.1920
MCF 10A BX-912
0.04
uM
LJP5
 72
hr
 513 9307 10401 0.8948 0.8893
MCF 10A Buparlisib
0.04
uM
LJP5
 72
hr
 513 10062 10401 0.9675 0.9658
MCF 10A Brivanib
0.04
uM
LJP5
 72
hr
 513 9764 10401 0.9387 0.9356
MCF 10A XMD16-144
0.04
uM
LJP5
 72
hr
 513 8960 10401 0.8615 0.8543
MCF 10A WZ-4-145
0.04
uM
LJP6
 72
hr
 513 8831 10401 0.8491 0.8413
MCF 10A WH-4-025
0.04
uM
LJP5
 72
hr
 513 10673 10401 1.0261 1.0275
MCF 10A HG-6-64-01
0.04
uM
LJP6
 72
hr
 513 11110 10401 1.0682 1.0717
MCF 10A XMD11-85h
0.04
uM
LJP6
 72
hr
 513 9036 10401 0.8688 0.8620
MCF 10A OSI-027
0.04
uM
LJP6
 72
hr
 513 7223 10401 0.6944 0.6786
MCF 10A A443654
0.04
uM
LJP6
 72
hr
 513 4000 10401 0.3846 0.3527
MCF 10A Luminespib
0.04
uM
LJP5
 72
hr
 513 474 10401 0.0456 -0.0040
MCF 10A Alpelisib
0.04
uM
LJP5
 72
hr
 513 9455 10401 0.9090 0.9043
MCF 10A KIN001-043
0.04
uM
LJP6
 72
hr
 513 11127 10401 1.0698 1.0734
MCF 10A PIK-93
0.04
uM
LJP5
 72
hr
 513 10310 10401 0.9913 0.9908