LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Dasatinib
0.04
uM
LJP5
 72
hr
 929 2282 3228 0.7070 0.5886
Hs 578T Dovitinib
0.04
uM
LJP5
 72
hr
 929 2551 3228 0.7904 0.7056
Hs 578T Enzastaurin
0.04
uM
LJP5
 72
hr
 929 3281 3228 1.0165 1.0232
Hs 578T Pictilisib
0.04
uM
LJP6
 72
hr
 929 2559 3228 0.7927 0.7090
Hs 578T Gefitinib
0.04
uM
LJP6
 72
hr
 929 3235 3228 1.0021 1.0030
Hs 578T Geldanamycin
0.04
uM
LJP6
 72
hr
 929 2701 3228 0.8368 0.7709
Hs 578T GSK1059615
0.04
uM
LJP5
 72
hr
 929 3168 3228 0.9816 0.9742
Hs 578T Omipalisib
0.04
uM
LJP6
 72
hr
 929 1409 3228 0.4366 0.2088
Hs 578T GSK 690693
0.04
uM
LJP5
 72
hr
 929 2630 3228 0.8149 0.7401
Hs 578T HG-5-113-01
0.04
uM
LJP5
 72
hr
 929 3070 3228 0.9512 0.9315
Hs 578T HG-5-88-01
0.04
uM
LJP6
 72
hr
 929 3095 3228 0.9588 0.9421
Hs 578T Linifanib
0.04
uM
LJP6
 72
hr
 929 3168 3228 0.9814 0.9739
Hs 578T Linsitinib
0.04
uM
LJP5
 72
hr
 929 3174 3228 0.9834 0.9766
Hs 578T Mitoxantrone
0.04
uM
LJP6
 72
hr
 929 1329 3228 0.4117 0.1739
Hs 578T MK2206
0.04
uM
LJP6
 72
hr
 929 2927 3228 0.9067 0.8690
Hs 578T Nintedanib
0.04
uM
LJP6
 72
hr
 929 2947 3228 0.9131 0.8780
Hs 578T NU7441
0.04
uM
LJP5
 72
hr
 929 3193 3228 0.9893 0.9850
Hs 578T NVP-TAE684
0.04
uM
LJP6
 72
hr
 929 2877 3228 0.8915 0.8476
Hs 578T Palbociclib
0.04
uM
LJP6
 72
hr
 929 2313 3228 0.7165 0.6019
Hs 578T PD184352
0.04
uM
LJP5
 72
hr
 929 2483 3228 0.7692 0.6759
Hs 578T Pelitinib
0.04
uM
LJP5
 72
hr
 929 3215 3228 0.9961 0.9945
Hs 578T PF477736
0.04
uM
LJP5
 72
hr
 929 3161 3228 0.9793 0.9710
Hs 578T PF562271
0.04
uM
LJP6
 72
hr
 929 2878 3228 0.8918 0.8480
Hs 578T Nilotinib
0.37
uM
LJP5
 72
hr
 929 3705 3228 1.1480 1.2078
Hs 578T Neratinib
0.37
uM
LJP5
 72
hr
 929 2418 3228 0.7493 0.6479