LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 AZD7762
3.33
uM
LJP6
 72
hr
 868 683 3486 0.1959 -0.0707
MCF 10A PHA-665752
10.0
uM
LJP5
 72
hr
 513 684 10401 0.0658 0.0173
Hs 578T A443654
10.0
uM
LJP6
 72
hr
 929 684 3228 0.2119 -0.1067
MCF 10A CGP60474
0.37
uM
LJP5
 72
hr
 513 685 10401 0.0659 0.0174
MCF 10A PD0325901
0.12
uM
LJP6
 72
hr
 513 687 10401 0.0661 0.0176
SK-BR-3 Geldanamycin
10.0
uM
LJP6
 72
hr
 1476 688 3694 0.1864 -0.3554
MCF 10A Mitoxantrone
0.12
uM
LJP6
 72
hr
 513 690 10401 0.0663 0.0179
MCF 10A A443654
0.37
uM
LJP6
 72
hr
 513 692 10401 0.0666 0.0181
MDA-MB-231 Celastrol
3.33
uM
LJP6
 72
hr
 868 692 3486 0.1986 -0.0671
MCF 10A Canertinib
3.33
uM
LJP6
 72
hr
 513 694 10401 0.0668 0.0183
MCF 10A CGP60474
1.11
uM
LJP5
 72
hr
 513 694 10401 0.0667 0.0183
MCF7 Alvocidib
0.37
uM
LJP6
 72
hr
 1235 694 4156 0.1671 -0.1852
MDA-MB-231 CGP60474
0.37
uM
LJP5
 72
hr
 868 695 3486 0.1995 -0.0659
Hs 578T Foretinib
10.0
uM
LJP5
 72
hr
 929 697 3228 0.2161 -0.1007
MDA-MB-231 NVP-TAE684
10.0
uM
LJP6
 72
hr
 868 698 3486 0.2003 -0.0648
MCF 10A GW843682X
10.0
uM
LJP6
 72
hr
 513 701 10401 0.0674 0.0190
MCF7 HG-6-64-01
10.0
uM
LJP6
 72
hr
 1235 701 4156 0.1688 -0.1827
MCF 10A GW843682X
3.33
uM
LJP6
 72
hr
 513 701 10401 0.0674 0.0190
MCF 10A AZD 5438
3.33
uM
LJP6
 72
hr
 513 704 10401 0.0677 0.0193
MCF 10A Pictilisib
10.0
uM
LJP6
 72
hr
 513 704 10401 0.0677 0.0193
MCF7 Seliciclib
10.0
uM
LJP5
 72
hr
 1235 706 4156 0.1699 -0.1813
MDA-MB-231 SB590885
10.0
uM
LJP5
 72
hr
 868 706 3486 0.2026 -0.0618
MCF 10A Neratinib
1.11
uM
LJP5
 72
hr
 513 712 10401 0.0685 0.0201
MDA-MB-231 Pelitinib
10.0
uM
LJP5
 72
hr
 868 713 3486 0.2045 -0.0592
MCF 10A Omipalisib
0.04
uM
LJP6
 72
hr
 513 714 10401 0.0687 0.0203