LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 4840 | 4156 | 1.1647 | 1.2344 |
| SK-BR-3 | PLX-4720 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4215 | 3694 | 1.1411 | 1.2351 |
| SK-BR-3 | PD173074 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 4220 | 3694 | 1.1424 | 1.2372 |
| SK-BR-3 | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4221 | 3694 | 1.1426 | 1.2376 |
| MCF7 | CP466722 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4851 | 4156 | 1.1672 | 1.2379 |
| SK-BR-3 | CGP60474 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4222 | 3694 | 1.1429 | 1.2381 |
| SK-BR-3 | SU11274 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4224 | 3694 | 1.1435 | 1.2390 |
| SK-BR-3 | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4225 | 3694 | 1.1439 | 1.2398 |
| Hs 578T | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 929 | 3783 | 3228 | 1.1719 | 1.2414 |
| Hs 578T | Sorafenib | 0.04 | uM | LJP6 | 72 | hr | 929 | 3783 | 3228 | 1.1720 | 1.2415 |
| SK-BR-3 | XL147 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4230 | 3694 | 1.1453 | 1.2420 |
| Hs 578T | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 929 | 3785 | 3228 | 1.1725 | 1.2423 |
| SK-BR-3 | Saracatinib | 0.04 | uM | LJP6 | 72 | hr | 1476 | 4233 | 3694 | 1.1459 | 1.2431 |
| SK-BR-3 | NVP-AEW541 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4233 | 3694 | 1.1461 | 1.2434 |
| Hs 578T | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 929 | 3796 | 3228 | 1.1760 | 1.2472 |
| MCF7 | SU11274 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4880 | 4156 | 1.1743 | 1.2481 |
| SK-BR-3 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 4251 | 3694 | 1.1508 | 1.2512 |
| Hs 578T | Sorafenib | 0.12 | uM | LJP6 | 72 | hr | 929 | 3812 | 3228 | 1.1810 | 1.2542 |
| MCF7 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 4899 | 4156 | 1.1787 | 1.2543 |
| SK-BR-3 | PD173074 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 4269 | 3694 | 1.1557 | 1.2594 |
| MCF7 | Pelitinib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4915 | 4156 | 1.1827 | 1.2600 |
| MCF7 | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4925 | 4156 | 1.1851 | 1.2633 |
| SK-BR-3 | XL147 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 4284 | 3694 | 1.1598 | 1.2662 |
| MCF7 | PIK-93 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4937 | 4156 | 1.1880 | 1.2676 |
| SK-BR-3 | PD173074 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 4293 | 3694 | 1.1621 | 1.2701 |